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While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights
The 'Thin on the Outside Fat on the Inside' TOFI_Asia study found Asian Chinese to be more susceptible to Type 2 Diabetes (T2D) compared to European Caucasians matched for gender and body mass index (BMI). This was influenced by degree of visceral adipose deposition and ectopic fat accumulation in k...
2022-10-12 | MTBLS5568 | MetaboLights
The goal of this study was to investigate the effect of a short-term nutritional intervention on gene expression in adipose tissue from lean and overweight subjects
ORGANISM(S): Homo sapiens 
It was hypothesized that specific dietary components are able to reduce low grade inflammation, as well as metabolic stress and oxidative stress in overweight men
ORGANISM(S): Homo sapiens 
Obesity is a chronic inflammatory condition which leads to a change in the production of adipokines and cytokines that can be found in blood plasma and saliva. It increases the risk for periodontal and cardiovascular diseases, hypertension, dyslipidemia, type 2 Diabetes Mellitus, cancer and others. ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-15 | PXD017165 | Pride
Distinct whole blood transcriptome profile of children with metabolic healthy overweight/obesity compared to metabolic unhealthy overweight/obesity
Hypertension state and overweight/obesity affect the transcriptome alternation in Human Visceral Adipose Tissue
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