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Atrial fibrillation (AF), the most prevalent clinical arrhythmia, imposes a major global health burden through elevated risks of stroke, heart failure, and mortality. Lysine propionylation (Kpr) is mainly involved in metabolic regulation and plays an important role in cardiac pathophysiology. Howeve...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-08-07 | PXD067998 | Pride
Single cell analysis of the tumor microenvironment in OXCT1-deficient-macrophages hepatocellular carcinoma mice (PRJCA018005)
Chemotherapy is often combined with surgery for muscle invasive and non-muscle invasive bladder cancer. However, 70% of the patients recur within 5 years. Metabolic reprogramming is an emerging hallmark in cancer chemoresistance. Here, we report a gemcitabine resistance mechanism which promotes canc...
ORGANISM(S): Homo sapiens 
2025-01-02 | GSE280095 | GEO
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