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ProteomicsA General Approach for Activity-based Protein Profiling of Oxidoreductases with Redox-differentiated Diarylhalonium Warheads
Activity-based protein profiling (ABPP) is a unique proteomic tool for measuring the activity of enzymes in their cellular context, which has been well established for enzyme classes exhibiting a characteristic nucleophilic residue (e.g. hydrolases). In contrast, the enzyme class of oxidoreductases ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD043873 | Pride
Oxidoreductase probe Mouse liver; Activity-based protein profiling 
UnknownA highly selective fluorescent probe for human NAD(P)H:quinone oxidoreductase 1 (hNQO1) detection and imaging in living tumor cells.
Not available
S-EPMC9070553 | biostudies-literature
UnknownCharacteristics of ovarian cancer detection by a near-infrared fluorescent probe activated by human NAD(P)H: quinone oxidoreductase isozyme 1 (hNQO1).
Not available
S-EPMC5617415 | biostudies-literature
UnknownGenotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.
Not available
S-EPMC3380101 | biostudies-literature
ProteomicsPhotoaffinity ligand of Cystic Fibrosis corrector VX-445 identifies SCCPDH as an off-target
Cystic fibrosis (CF) pharmacological correctors such as VX-445 are used in combinations as highly effective modulator therapy (HEMT) at CF clinics due to their efficacy in improving Cystic Fibrosis transmembrane conductance regulator (CFTR) protein trafficking and function. Yet, several side-effects...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD060898 | Pride
Elexacaftor Cystic fibrosis (cf) Vu439 Click chemistry Target identification Cystic fibrosis transmembrane conductance regulator (cftr) Off-target Mass spectrometry (ms) Proteomics Diazirine Metabolomics Chemoproteomics Corrector Photoaffinity ligand (pal) Vx-445 Saccharopine dehydrogenase-like oxidoreductase (sccpdh) 
Unknownns-μs Time-Resolved Step-Scan FTIR of ba₃ Oxidoreductase from Thermus thermophilus: Protonic Connectivity of w941-w946-w927.
Not available
S-EPMC5085690 | biostudies-literature
UnknownBinding Interface and Electron Transfer Between Nicotine Oxidoreductase and Its Cytochrome c Electron Acceptor.
Not available
S-EPMC10163435 | biostudies-literature
UnknownMicroRNA-218-5p affects lung adenocarcinoma progression through targeting endoplasmic reticulum oxidoreductase 1 alpha.
Not available
S-EPMC9161986 | biostudies-literature
UnknownPredicting 19 F NMR Chemical Shifts: A Combined Computational and Experimental Study of a Trypanosomal Oxidoreductase-Inhibitor Complex.
Not available
S-EPMC7496126 | biostudies-literature
UnknownMechanistic reappraisal of early stage photochemistry in the light-driven enzyme protochlorophyllide oxidoreductase.
Not available
S-EPMC3458894 | biostudies-literature
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