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Natural systems produce various γ-dicarbonyl-bearing compounds that can covalently modify lysine in protein targets via the classic Paal-Knorr reaction. Among them is a unique class of lipid-derived electrophiles - isoketals that exhibit high chemical reactivity and critical biological functions. Ho...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-15 | PXD028270 | Pride
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