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ProteomicsPan-cancer plasma proteome profiling using SIS recombinant protein fragments reveals downregulation of proteins interacting with immunoglobulins in multiple myeloma
Mass spectrometry based on Data Independent Acquisition (DIA) strategies has developed into powerful tools suitable for precision medicine applications. Assays performed in this setting provide confident protein identification and precise quantification on an absolute scale when combined with stable...
ORGANISM(S): Homo Sapiens 
2024-07-03 | PXD037946 | panorama
ProteomicsThe Pan-Cancer Proteome Atlas, a mass spectrometry-based landscape for understanding tumor biology and discovering biomarkers and therapeutic targets
Next-generation quantitative proteomics based on data-independent acquisition mass spectrometry (DIA-MS) enables large-scale sample profiling, a necessity for (pre)clinical studies with heterogeneous samples. To date, most cancer protein profiling studies have focussed on a single cancer type. Here ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-30 | PXD054790 | Pride
Pan-cancer proteome Dia-ms Single shot Mass spectrometry-based proteomics 
ProteomicsAnalytical insights from FFPE-based proteome profiling of 1,200 pan cancer cases
Proteome profiling of formalin-fixed paraffin-embedded (FFPE) specimens has gained traction in recent years for the analysis of human clinical material, notably cancer tissue for the discovery of molecular biomarkers. However, published reports so far focused on certain cancer entities and comprised...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-06-14 | MSV000095036 | MassIVE
ProteomicsPan-cancer proteomic map of 949 human cell lines (ProCan-DepMapSanger)
This pan-cancer cell line proteomic atlas comprises proteomic data acquired by data independent acquisition (specifically, SWATH) mass spectrometry for 949 cancer cell lines. Cell lines were processed in technical triplicate, with duplicates acquired on different mass spectrometers, alongside HEK293...
ORGANISM(S): Homo sapiens (Human) 
2022-07-13 | PXD030304 | Pride
Proteomics Dia Swath Cancer Cell line 
UnknownTowards routine proteome profiling of FFPE tissue: insights from a 1,220-case pan-cancer study.
Not available
S-EPMC11697351 | biostudies-literature
ProteomicsIntegrated analysis of proteome and transcriptome profiling reveals pan-cancer-associated pathways and molecular biomarkers
Understanding dysregulated genes and pathways in cancer is critical for precision oncology. Integrating mass spectrometry-based proteomic data with transcriptomic data presents unique opportunities for systematic analyses of dysregulated genes and pathways in pan-cancer. Here, we compiled a comprehe...
ORGANISM(S): Homo Sapiens 
2024-12-24 | PXD059207 |
UnknownIntegrated Analysis of Proteome and Transcriptome Profiling Reveals Pan-Cancer-Associated Pathways and Molecular Biomarkers.
Not available
S-EPMC11907456 | biostudies-literature
ProteomicsThe pan-cancer lncRNA PLANE regulates an alternative splicing program and promotes cancer pathogenesis
Proteome analysis of Biotin- PLANE pull-down assays
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022747 |
UnknownA pan-cancer proteomic perspective on The Cancer Genome Atlas.
Not available
S-EPMC4109726 | biostudies-literature
UnknownPan-cancer proteomic map of 949 human cell lines.
Not available
S-EPMC9387775 | biostudies-literature
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