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ProteomicsProteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms
Pancreatic neuroendocrine neoplasms (PNENs) are biologically and clinically heterogeneous neoplasms. We used quantitative global proteomic analysis on 40 PNENs to compliment paired transcriptome data.
ORGANISM(S): Homo sapiens (Human) 
2021-11-30 | PXD024175 | Pride
Pancreatic neuroendocrine neoplasms 
ProteomicsProteogenomic characterization of pancreatic neuroendocrine tumor
To characterize pancreatic neuroendocrine tumor at protein level, we performed mass spectromery-based proteome analysis using clinical FFPE tissue samples.
ORGANISM(S): Homo sapiens (Human) 
2024-07-10 | PXD034571 | Pride
Human Tissue Pancreatic neuroendocrine tumor 
TranscriptomicsVitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) has been attributed to intrinsic resistance to chemotherapy and a growth-permissive tumor microenvironment. Quiescent pancreatic stellate cells (PSCs) are neuroendocrine, nestin-positive, lipid-accumulating cells whose homologues i...
ORGANISM(S): Mus musculus 
2014-10-03 | E-GEOD-43770 | biostudies-arrayexpress
ProteomicsLC-MS of Human Blood of Pancreatic neuroendocrine tumors
Pancreatic Neuroendocrine tumors are challenging to diagnose and often detected at advanced stages due to lack of specific and sensitive biomarkers. This study utilized proteomics as a valuable approach for cancer biomarker discovery, therefore, mass spectrometry-based proteomic profiling was conduc...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD045045 | Pride
Human Pancreatic neuroendocrine tumors Lc-ms Plasma 
UnknownUnmet needs in the international neuroendocrine tumor (NET) community: Assessment of major gaps from the perspective of patients, patient advocates and NET health care professionals.
Not available
S-EPMC7004101 | biostudies-literature
GenomicsGene expression profiling of pancreatic neuroendocrine carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm
Gene expression profiling of pancreatic neuroendocrine carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm
PRJNA1004639 | ENA
UnknownModelling Pancreatic Neuroendocrine Cancer: From Bench Side to Clinic.
Not available
S-EPMC7693644 | biostudies-literature
GenomicWhole Exome Sequencing of Pancreatic Neuroendocrine Tumors

Pancreatic neuroendocrine tumors (PNETs), often referred to as "islet cell tumors", are neuroendocrine neoplasms that arise from cells of the endocrine and nervous system within the pancreas. These rare tumors which originate from the pancreatic islet are divided into many categories and are ofte...

phs000871 | dbGaP
TranscriptomicsGene expression profiles of thymic neuroendocrine tumors (carcinoids) with ectopic ACTH syndrome
Although there has been increased knowledge about the molecular biology of neuroendocrine tumors (NETs), little is known about thymic carcinoids and even less about those with excessive hormone disorders, such as ectopic ACTH syndrome. This study was designed to gain insights into molecular networks...
ORGANISM(S): Homo sapiens 
2009-08-13 | E-GEOD-17619 | biostudies-arrayexpress
GenomicsDynamic epigenetic regulation by menin during pancreatic islet tumor formation
loss of Men1 in mouse pancreatic islet cells alters the epigenetic landscape of a subset of target genes. H3K4me3 ChIP-seq from either mouse pancreatic islets or mouse pancreatic islet tumors harvested at different stages.
ORGANISM(S): Mus musculus 
2015-04-16 | E-GEOD-63020 | biostudies-arrayexpress
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