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TGF? activates a signal transduction cascade that results in the transcription of genes, primarily through the DNA-binding transcription factor SMAD3. The objective of this study is to identify SMAD3 binding targets and the molecular pathways affected by the TGF?1/SMAD3 signal transduction on a geno...
ORGANISM(S): Homo sapiens 
This a model from the article: Using Physiome standards to couple cellular functions for rat cardiac excitation-contraction. Terkildsen JR, Niederer S, Crampin EJ, Hunter P, Smith NP. Exp Physiol. (2008) 93(7) pp 919-29; Pubmed ID: 18344258 ...
2005-01-01 | MODEL7893871775 | BioModels
Tomato leafminer (Tuta absoluta) is a major pest of solanaceous plant species and causes heavy economic losses to the tomato crop. T. absoluta have been developed resistance to many chemical insecticides and have serious impacts on human health as well as environment. To overcome the ill effects of ...
ORGANISM(S): Bombyx mori (Silk moth) 
2022-07-05 | PXD029374 | Pride
Idiopathic pulmonary fibrosis (IPF) is an untreatable fibrotic lung disease characterized by fibroblast proliferation and epithelial mesenchymal transition. The expression and role of microRNAs (miRNA) has not been studied in IPF. Using miRNA expression microarrays we identified 46 differentially ex...
ORGANISM(S): Homo sapiens 
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