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ProteomicsProteomic analysis of small extracellular vesicles (sEVs) derived from primary keratinocytes cultured in different calcium concentrations, treated with a peanut allergen extract and atopic dermatitis (AD)-relevant cytokines
Epidermal keratinocytes are key for maintenance of the integrity of the epidermis. One of the main drivers of keratinocyte differentiation is the calcium gradient; calcium concentration gradually increases towards the outer layers of the epidermis. Atopic dermatitis (AD) is a disorder associated wit...
ORGANISM(S): Homo sapiens (Human) 
2022-06-07 | PXD031729 | Pride
Extracellular vesicles Keratinocyte Atopic dermatitis Allergy 
ProteomicsProteomic analysis of small extracellular vesicles isolated from human blood plasma
Exosomes are small, lipid-rich membrane vesicles secreted by all nucleated cells. These vesicles carry a variety of cargo including nucleic acids, proteins and lipids. Due to their size and flexibility, exosomes can enter the circulation and therefore serve as means of communication between distant...
ORGANISM(S): Homo sapiens (Human) 
2023-06-07 | PXD036724 | Pride
Exosomes Extracellular vesicles Blood plasma 
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