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ProteomicsAcetylation level of Pannexin 1 lysine residues following alpha 1 adrenoceptor activation
Pannexin 1 (Panx1) channels can be activated by alpha 1 adrenoceptor-induced pathways for the sympathetic regulation of blood pressure; however, the molecular mechanisms for this form of Panx1 channel activation remain elusive. To identify potential acetyl-lysine residue(s) of Panx1 channels that mi...
ORGANISM(S): Homo sapiens (Human) 
2021-07-16 | PXD025912 | Pride
Alpha 1 adrenoceptor Pannexin Acetylation Panx1 Silac Phenylephrine 
ProteomicsPANNEXIN-1 CHANNEL REGULATES NUCLEAR CONTENT PACKAGING INTO APOPTOTIC BODIES AND THEIR SIZE
Apoptotic bodies (ApoBDs), which are large extracullular vesicles exclusively released by apoptotic cells, possess therapeutically exploitable properties including biomolecule loadability and transferability. However, current limited understanding of ApoBD biology has hindered its exploration for cl...
ORGANISM(S): Homo sapiens (Human) 
2021-04-08 | PXD023988 | Pride
Pannexin 1 Apoptotic bodies Extracellular vesicles Nuclear proteins Dna Cargo sorting 
UnknownCryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Not available
S-EPMC10997603 | biostudies-literature
ProteomicsPannexin 1 interactome in Rhabdomyosarcoma
We have recently reported the down-regulation of pannexin 1 (PANX1) levels in rhabdomyosarcoma (RMS) and that restoration of its expression inhibits the progression of embryonal (eRMS) and alveolar (aRMS) rhabdomyosarcoma in vitro and in vivo. While we have shown that this PANX1-mediated inhibition ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-30 | MSV000084867 | MassIVE
GenomicsPannexin 1 phosphorylation sites differentially modulate channel activity and physiological outcomes
Pannexin 1 phosphorylation sites differentially modulate channel activity and physiological outcomes
PRJNA1477793 | ENA
UnknownPannexin 1 Modulates Axonal Growth in Mouse Peripheral Nerves.
Not available
S-EPMC5702652 | biostudies-literature
UnknownPannexin 1 activity in astroglia sets hippocampal neuronal network patterns.
Not available
S-EPMC9728857 | biostudies-literature
UnknownA permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP.
Not available
S-EPMC2643853 | biostudies-literature
UnknownPannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma.
Not available
S-EPMC12333905 | biostudies-literature
UnknownPannexin protein expression in the rat middle cerebral artery.
Not available
S-EPMC3290039 | biostudies-literature
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