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Pannexin 1 (Panx1) channels can be activated by alpha 1 adrenoceptor-induced pathways for the sympathetic regulation of blood pressure; however, the molecular mechanisms for this form of Panx1 channel activation remain elusive. To identify potential acetyl-lysine residue(s) of Panx1 channels that mi...
ORGANISM(S): Homo sapiens (Human) 
2021-07-16 | PXD025912 | Pride
Apically localized PANX1 impacts neuroepithelial expansion in human cerebral organoids
Dysfunctional paracrine signaling through Pannexin 1 (PANX1) channels is linked to several adult neurological pathologies and emerging evidence suggests that PANX1 plays an important role in human brain development. It remains unclear how early PANX1 influences brain development, or how loss of PANX...
ORGANISM(S): Homo sapiens 
2023-12-12 | GSE249624 | GEO
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