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ProteomicsPlatelet proteome in Essential Thrombocythemia
Platelets from healthy donors (HD) and Essential Thrombocythemia (ET) patients were isolated from peripheral blood. The HD were treated with low dose aspirin (100mg) once daily and blood samples were collected before and after treatment. ET patients from different mutational backgrounds (JAK2 V617F,...
ORGANISM(S): Homo sapiens (Human) 
2026-09-09 | PXD052171 | Pride
Mass spectrometry Platelets 
TranscriptomicsTAF10 interacts with the GATA1 transcription factor and controls mouse erythropoiesis
We have ablated TAF10 in the erythroid compartment only by crossing the TAF10lox mice with the EpoR-Cre mice and we have studied the development of the erythroid cells in vivo. TAF10 ablation led to embryonic death at E13.5 while at E12.5 there was a clear developmental defect which was reflected in...
ORGANISM(S): Mus musculus 
2015-04-21 | E-GEOD-68083 | biostudies-arrayexpress
ProteomicsTAF10 interacts with GATA1 transcription factor and controls mouse erythropoiesis
The stoichiometries of TFIID and SAGA (TAF10-containing complexes) have been quantified in mouse and human erythroid cells. TAF10 immunoprecipitations (IPs) have been carried out in erythroid cells at different stages of differentiation and development followed by quantitative mass spectrometry (MS)...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2015-04-21 | PXD000729 | Pride
Gata-1 Taf10 
ProteomicsProteomic analysis of platelets from Essential Thrombocythemia patients links metabolism to platelet reactivity
Platelets from three healthy donors (HD) and eighteen Essential Thrombocythemia (ET) patients were isolated from peripheral blood. The three HD were treated with low dose aspirin (100mg) once daily and blood samples were collected before and after treatment. ET patients from different mutational bac...
ORGANISM(S): Homo sapiens (Human) 
2026-09-09 | PXD050550 | Pride
Essential thrombocythemia Aspirin Platelet activation Mitochondria Calreticulin 
OtherTAF10 interacts with GATA1 transcription factor and controls mouse erythropoiesis.
Data from ProteomeXchange, PXD ID: PXD000729. Experiment: hs, file: F049331.dat-pride.pride.mgf. Published as part of Mol Cell Biol. 2015 Apr 13 . From the Abstract: {{i}} The ordered assembly of a functional pre-initiation complex (PIC), composed of general transcription factors (GTFs), is a prere...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320015002 | GPMDB
Resource Reanalysis 
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