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We have shown that decreasing psmd9 expression effects lipid metabolism in vivo and were interested in investigating the pathways by which psmd9 elicited these changes. To investigate these mechanisms, we performed proteomic analyses on the livers from C57 and DBA mice that had been treated with ant...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-14 | PXD010759 | Pride
Hepatosteatosis underlies several diseases including type 2 diabetes, cardiovascular disease and liver disease. Unfortunately, our understanding of the contributing pathways that initiate and advance hepatosteatosis to subsequent complications is still poorly understood. Here, we take advantage of r...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-05 | PXD010818 | Pride
Obesity is a major risk factor underlying the development of metabolic disease and a growing public health concern globally. Strategies to promote skeletal muscle metabolism can be effective to limit the progression of metabolic disease. Here, we demonstrate that the levels of the Hippo pathway tran...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-25 | PXD024379 | Pride
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