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UnknownFlow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
Not available
S-EPMC7206797 | biostudies-literature
ProteomicsRe-expression of SMARCA4/BRG1 in Small Cell Carcinoma of Ovary, Hypercalcemic Type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer. SCCOHT tumors have inactivating mutations in SMARCA4 (BRG1), one of the two mutually exclusive ATPases of the SWI/SNF chromatin remodeling complex. To address the role that BRG1 loss plays...
ORGANISM(S): Homo sapiens (Human) 
2021-01-15 | PXD014134 | Pride
Ovarian carcinoma smarca4 
ProteomicsMag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome
Membrane-bound particles in plasma are composed of exosomes, microvesicles, and apoptotic bodies and represent ~1-2% of the total protein composition. Proteomic interrogation of this subset of plasma proteins augments the representation of tissue-specific proteins, representing a “liquid biopsy,” wh...
ORGANISM(S): Homo Sapiens 
PXD042947 | panorama
TranscriptomicsAryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC) transplants remains limited by the ability to expand these cells ex vivo. An unbiased screen with primary human HSCs identified a purine derivative, StemRegenin 1 (SR1), that promotes the ex vivo expansion...
ORGANISM(S): Homo sapiens 
2011-04-04 | E-GEOD-28359 | biostudies-arrayexpress
MetabolomicsAccumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex
Secondary metabolites are involved in the plant stress response. Among these are scopolin and its active form scopoletin, which are coumarin derivatives associated with reactive oxygen species scavenging and pathogen defence. Here we show that in Arabidopsis thaliana, scopolin accumulation can be in...
2018-02-05 | MTBLS389 | MetaboLights
UnknownProteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.
Not available
S-EPMC8563374 | biostudies-literature
ProteomicsProteomics of campylobacter exposed to host Caco-2 and INT407 intestinal cells
Comparison of Campylobacter proteome in MH media with and without deoxycholic acid, in presence of FBS or after being exposed to INT 407 and Caco2 intestinal epithelial cells.
ORGANISM(S): Campylobacter jejuni 
2019-05-03 | PXD009817 | Pride
Intestine Proteomics Campylobacter 
GenomicWomen's Interagency HIV Study (WIHS)

The Women's Interagency HIV Study (WIHS), a multicenter, prospective study, was established in August 1993 to carry out comprehensive investigations of the impact of HIV infection and its clinical, laboratory, and psychosocial effects in women. The purpose of this study is to collect and eval...

phs001503 | dbGaP
ProteomicsNovel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
Novel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
ORGANISM(S): Homo sapiens (Human) 
2025-12-10 | PXD056257 | Pride
Nrf2 Keap1 Cul3 
UnknownSeven-year follow-up assessment of cardiac function in NSABP B-31, a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel (ACP) with ACP plus trastuzumab as adjuvant therapy for patients with node-positive, human epidermal growth factor receptor 2-positive breast cancer.
Not available
S-EPMC3478574 | biostudies-literature
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