Parkinson`s disease

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Unknown (1559)
Transcriptomics (163)
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Homo sapiens (140)
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Organisms

Homo sapiens (19)
Mus musculus (6)
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Repository

biostudies-arrayexpress (164)
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geo (20)
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pride (15)
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Tissue

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Disease

Parkinson's disease (10)
Alzheimer's disease (2)
Lewy body dementia (2)
12 DAI with PepMV-EU isolate (1)
Glioma (1)
Bronchioloalveolar carcinoma of lung (1)
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N/a (1)
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Technology Type

Mass Spectrometry (15)
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Bottom-up proteomics (3)
Illumina HiSeq 2000 (2)
NMR spectroscopy assay (2)
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Instrument Platform

NextSeq 500 (8)
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NA (2)
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- (2)
Impact (2)
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Sequel (1)
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Illumina (1)
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Instrument (1)
6550 iFunnel Q-TOF LC/MS (1)
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Publication Date

2010 (20)
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2014 (17)
2013 (17)
2015 (16)
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2008 (13)
2011 (12)
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2018 (10)
2024 (9)
2017 (9)
2021 (8)
2019 (6)
2023 (4)
2009 (4)
2007 (4)
2020 (3)
2005 (2)
2004 (1)

UNIPROT ID/AC

1433B_HUMAN (2)
1433F_HUMAN (2)
1433G_HUMAN (2)
1433S_HUMAN (2)
1433T_HUMAN (2)
1433Z_HUMAN (2)
2A5A_HUMAN (2)
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3BP1_HUMAN (2)
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41_HUMAN (2)
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4ET_HUMAN (2)
4F2_HUMAN (2)
5HT1A_HUMAN (2)
5HT1B_HUMAN (2)
5HT2A_HUMAN (2)

CHEBI ID

CHEBI:13705 (3)
CHEBI:37054 (3)
CHEBI:4153 (3)
CHEBI:31011 (3)
CHEBI:64552 (3)
CHEBI:15724 (3)
CHEBI:18147 (3)
CHEBI:28847 (3)
CHEBI:15361 (3)
CHEBI:24996 (3)
CHEBI:40410 (3)
CHEBI:60645 (3)
CHEBI:37714 (3)
CHEBI:16283 (3)
CHEBI:4139 (3)
CHEBI:4167 (3)
CHEBI:16530 (3)
CHEBI:16919 (3)
CHEBI:17754 (3)
CHEBI:15729 (3)
CHEBI:17196 (3)
CHEBI:17115 (3)
CHEBI:16737 (3)
CHEBI:30915 (3)
CHEBI:15891 (3)
CHEBI:4208 (3)
CHEBI:16857 (3)
CHEBI:17191 (3)
CHEBI:15428 (3)
CHEBI:17268 (3)

Metabolite Name

L-Serine (5)
N-Acetylglycine (4)
Betaine (4)
Creatinine (4)
D-Glucose (4)
Creatine (4)
L-Carnitine (4)
L-Proline (4)
L-Phenylalanine (4)
L-Arginine (4)
L-Alanine (4)
L-GlutamicAcid (3)
2-Hydroxyisovalerate (3)
TMAO (3)
2-Oxoisovalerate (3)
L-Glycine (3)
D-Fucose (3)
Myo-Inositol (3)
Valerate (3)
3-Hydroxybutyrate (3)
Glycochenodeoxycholic acid (3)
Glucuronate (3)
D-Maltose (3)
Pyroglutamate (3)
Lactate (3)
2-Hydroxybutyrate (3)
Pyruvate (3)
L-Cystine (3)
Taurine (3)
L-Ornithine (3)

First Public Date

2018 (6)
2022 (5)
2026 (4)
2025 (3)
2024 (3)
2023 (3)
2021 (3)
2014 (2)
2020 (1)
2019 (1)
2017 (1)
2016 (1)

Study type

Transcription profiling by array (89)
RNA-seq of coding RNA (29)
ChIP-seq (9)
Proteomic profiling by array (7)
Transcription profiling by tiling array (6)
Other (5)
Comparative genomic hybridization by array (3)
RNA-seq of total RNA (3)
MicroRNA profiling by array (2)
Unknown experiment type (1)
ChIP-chip by tiling array (1)
Cell line - One-color microarray (1)
High-throughput sequencing (1)
RNAi profiling by array (1)
ChIP-chip by array (1)
Bisulfite-seq (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (251)
2024 (178)
2022 (170)
2021 (170)
2023 (139)
2020 (139)
2019 (122)
2018 (92)
2016 (88)
2017 (87)
2015 (71)
2014 (45)
2013 (35)
2026 (31)
2010 (25)
2012 (22)
2011 (17)
2009 (15)
2008 (14)
2007 (5)
2005 (4)
2004 (2)
2006 (1)

Lab affiliation

Department of Oncology-Pathology, Karolinska Institutet and Science for Life Laboratory, Stockholm, Sweden (2)
Center for Integrated Protein Science Munich (CIPSM) at the Department of Chemistry, Technische Universität München, Lichtenbergstraße 4, 85747 Garching b. München ( lab head ) (1)
Center for RNA Research, Institute for Basic Science, Seoul 08826, S. Korea School of Biological Sciences, Seoul National University, Seoul 08826, S. Korea (1)
Clinical Neuroproteomics Lab Navarrabiomed Proteored Pamplona, Spain (1)
Department of Biochemistry and Molecular Biology and Córdoba Maimónides Institute for Biomedical Research (IMIBIC), University of Córdoba (1)
Department of Biology, Faculty of Sciences-I, Lebanese University, Beirut, Lebanon (1)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Forensic Genetics and Biology, School of Forensic Medicine, China Medical University, Beijing, China (1)
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA (1)
Institute of Clinical Pharmacology, Goethe-University, Frankfurt am Main, Germany (1)
MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom (1)
Research and Innovation Centre, University of Regina, SK S4S OA2, Canada (1)
Ruhr-University Bochum, Zentrum für Proteindiagnostik (ProDi), Medizinisches Proteom-Center (MPC) (1)
Texas Tech University (1)

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Dimerisation and twist reversal of the Lewy fold in ?-synuclein mutants with Parkinson?s disease and dementia

Dominantly inherited missense and gene dosage mutations in SNCA, the ?-synuclein gene, cause familial forms of Parkinson?s disease and dementia. Here we report the structures of ?-synuclein filaments from the brains of such individuals. Pathogenic mutations A53T and G51D in SNCA gave rise to singlet...

ORGANISM(S): Homo sapiens (Human)

2026-10-22 | PXD082007 | Pride

Parkinson?s disease

Development of a new model of Parkinson´s disease

PRJNA1018840 | ENA

Palmitome analysis in parkinson´s disease

Proteomic analysis of the cortical palmitome derived from parkinson´s disease and control subjects

ORGANISM(S): Homo Sapiens (human)

PXD037352 | JPOST Repository

Quantitative interaction proteomics of neurodegenerative disease proteins.

Data from ProteomeXchange, PXD ID: PXD001942. File: 20130829_Orbi6_FaHo_SA_NN_SWEvsEV_Rep3_01.mzml. Published as part of Cell Rep. 2015 May 19;11(7):1134-46 . From the Abstract: {{i}} Several proteins have been linked to neurodegenerative disorders (NDDs), but their molecular function is not comple...

ORGANISM(S): Homo_sapiens_viruses, Human_female

GPM32320018141 | GPMDB

Resource Reanalysis

Targeted Bile Acid Metabolomic Profiling of Plasma Samples in Patients with Parkinson's Disease

Targeted LC-MS metabolomic profiling was performed on plasma samples from a validation cohort comprising 20 patients with Parkinson's disease and 20 healthy controls. The study aimed to verify altered circulating bile acid levels identified in the discovery cohort, assess correlations between bil...

2026-09-03 | MTBLS15429 | MetaboLights

Development of a new model of Parkinson´s disease

To get insight the molecular mechanism underlying neuronal loss in Parkinson´s disease. We performed gene expression profiling analysis using data obtained from RNA-seq of midbrain of mice injected with an AAV control or an AAV expressing human tyrosinase that induces neuromelanin accumulation and s...

ORGANISM(S): Mus musculus

2025-03-09 | GSE243520 | GEO

Integrative Metabolomics-GWAS Mendelian Randomization Reveals Causal Metabolic and Inflammatory Drivers of Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by a complex pathogenesis involving the interplay of multiple molecular and cellular pathways. In recent years, metabolic dysregulation and neuroinflammation have been recognized as key contributors to PD...

2025-11-05 | MTBLS13269 | MetaboLights

Proteomics on post-mortem human brain tissue of patients with Alzheimer`s, Parkinson`s and Lewy body dementias.

We have used HiRIEF (High Resolution Isoelectric Focusing) LC-MS proteomics with isobaric tags (TMT10plex) to compare 32 post-mortem human brains in the prefrontal cortex (Brodmann area 9) of prospectively followed patients with Alzheimer`s disease (AD), Parkinson`s disease with dementia (PDD), deme...

ORGANISM(S): Homo sapiens (Human)

2017-12-08 | PXD006122 | Pride

Synaptic Lewy body Proteomics Brain Prefrontal cortex Alzheimer Brodmann area 9 Parkinson Hirief Lcms Human

Sex differences modulate blood metabolome profiles in Parkinson’s disease patients harbouring rare genetic variants

Background: Recent findings from our group indicate that sex differences in Parkinson's disease (PD) patients with idiopathic conditions or carrying pathogenic mutations significantly influence the blood occurrence of D and L-amino acids, lipids, antioxidants, and energy-related metabolites when ...

2026-06-26 | MTBLS12746 | MetaboLights

GBA1 regulates the CLEAR network through Calcineurin and TFEB in cellular models of Parkinson´s disease

PRJNA485885 | ENA

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