Sort   by:  
 Page size 
TranscriptomicssnRNA data of Brain section from Parkinson Mouse Model based on inducible expression of human a-syn constructs
Using 6-months, 16-months, and 24-months old mice of a inducible expression of human a-syn constructs based Parkinson mouse model, we produced a single nucleus RNA dataset by cutting 0mm Bregma to -5mm Bregma. The Chromium 3’ Single Cell Library Kit (10x Genomics) was used and Sequencing was perform...
ORGANISM(S): Mus musculus 
2025-03-15 | E-MTAB-14889 | biostudies-arrayexpress
GenomicsInternational Genetics of Parkinson Disease Progression (IGPP) Consortium GWAS Summary Results
To characterize how genetic variation influences the progression of Parkinson’s disease to dementia, which is a major determinant for quality of life, we performed a longitudinal genome-wide survival study (GWSS). Risk profile analysis was performed with a novel polygenic hazard score in longit...
EGAS00001005110 | EGA
UnknownAssociation of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression.
Not available
S-EPMC8060834 | biostudies-literature
TranscriptomicssnRNA data of Brain section from Parkinson Mouse Model based on inducible expression of human a-syn constructs including conditions with pharmacological CDC42 inhibition
Using 6-months, 16-months, and 24-months old mice of a inducible expression of human a-syn constructs based Parkinson mouse model, we produced a single nucleus RNA dataset by cutting 0mm Bregma to -5mm Bregma. The Chromium 3’ Single Cell Library Kit (10x Genomics) was used and Sequencing was perform...
ORGANISM(S): Mus musculus 
2026-08-14 | E-MTAB-17455 | biostudies-arrayexpress
TranscriptomicssnRNA Visium Spatial data of Brain section from Parkinson Mouse Model based on inducible expression of human a-syn constructs 23 months
Using 23-months old mice of a inducible expression of human a-syn constructs based Parkinson mouse model, we produced a single nucleus RNA dataset by cutting 0mm Bregma to -5mm Bregma. The Chromium 3’ Single Cell Library Kit (10x Genomics) was used and Sequencing was performed on a NovaSeq 6000. P...
ORGANISM(S): Mouse 
2025-06-01 | E-MTAB-15158 | biostudies-arrayexpress
UnknownMetabolite changes in prefrontal lobes and the anterior cingulate cortex correlate with processing speed and executive function in Parkinson disease patients.
Not available
S-EPMC9338382 | biostudies-literature
UnknownAssociation Between Antiepileptic Drugs and Incident Parkinson Disease.
Not available
S-EPMC9857018 | biostudies-literature
UnknownEffect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial.
Not available
S-EPMC4349346 | biostudies-literature
TranscriptomicsBulk-RNA of MACS isolated Microglia from a Parkinson Mouse Model brain from young and old mice and Parkinson and Control
Microglia are increasingly recognized as active drivers of Parkinson's disease (PD), contributing to neuroinflammation, α-synuclein clearance, and dopaminergic neuron loss. Because aging is the strongest risk factor for PD and independently shifts microglia toward a primed, pro-inflammatory state, d...
ORGANISM(S): Mus musculus 
2026-06-17 | E-MTAB-17136 | biostudies-arrayexpress
UnknownMeasuring disease progression in early Parkinson disease: the National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) experience.
Not available
S-EPMC4188544 | biostudies-literature
Sort   by:  
 Page size