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UnknownSmooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE<sup>-/-</sup> mice.
Not available
S-EPMC9307802 | biostudies-literature
UnknownA shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses.
Not available
S-EPMC11535224 | biostudies-literature
ProteomicsAuto-phosphorylation at serine 166 regulates RIP kinase 1 mediated cell death and inflammation
Receptor interacting kinase 1 (RIPK1) regulates cell death and inflammatory responses downstream of TNFR1 and other receptors, and has been implicated in the pathogenesis of inflammatory and degenerative diseases. RIPK1 kinase activity induces cell death by activating apoptosis and necroptosis, howe...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-23 | PXD014097 | Pride
Inflammation Cell death Phosphorylation 
UnknownEpidermal p65/NF-κB signalling is essential for skin carcinogenesis.
Not available
S-EPMC4119358 | biostudies-literature
ProteomicsMitochondria regulate dietary lipid processing in enterocytes
Digested dietary fats are taken up, processed and transported by enterocytes to supply the body with lipids. Most absorbed lipids are assembled into pre-chylomicrons in the endoplasmic reticulum (ER) of enterocytes, which are then transported to the Golgi for maturation and subsequent secretion to t...
ORGANISM(S): Mus musculus (Mouse) 
2023-12-21 | PXD026934 | Pride
Golgi Lipid metabolism Mitochondria Small intestine Enterocyctes Dars2 Er 
UnknownZBP1 causes inflammation by inducing RIPK3-mediated necroptosis and RIPK1 kinase activity-independent apoptosis.
Not available
S-EPMC11239871 | biostudies-literature
UnknownIKKε and TBK1 prevent RIPK1 dependent and independent inflammation.
Not available
S-EPMC10761900 | biostudies-literature
TranscriptomicsTranscription profiling of brain from mice with multiple sclerosis, Alzheimers disease and permanent mid-cerebral artery occlusion from stroke to compare of gene expression changes characterizing these three different central nervous system pathologies
Three mouse models of human central nervous system pathologies were selected for analyzing gene expression changes compared to wild type normal brain. The selected models are: TgAPP23 for Alzheimerï¾’s disease (see Sturchler-Pierrat, C., Abramowski, D., Duke, M., Wiederhold, K.H., Mistl, C., Rothac...
ORGANISM(S): Mus musculus 
2008-07-12 | E-MTAB-1 | biostudies-arrayexpress
UnknownOTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice.
Not available
S-EPMC8501112 | biostudies-literature
UnknownNEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer.
Not available
S-EPMC10070460 | biostudies-literature
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