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ProteomicsAlternate covalent form of platelet αIIbβ3
The αIIbβ3 integrin receptor coordinates platelet adhesion, activation and mechanosensing in thrombosis and haemostasis. Using differential cysteine alkylation and mass spectrometry, we have identified a disulfide bond in the αIIb subunit linking cysteines 490 and 545 that is missing in about one in...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025907 | Pride
Αiibβ3 Platelet Disulfide Covalent Integrin 
UnknownAn alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function.
Not available
S-EPMC8532129 | biostudies-literature
UnknownPoint of care INR monitoring in cyanotic congenital heart disease-related compensatory erythrocytosis.
Not available
S-EPMC12907891 | biostudies-literature
UnknownIntracoronary thrombolysis in ST-elevation myocardial infarction: a systematic review and meta-analysis.
Not available
S-EPMC11287581 | biostudies-literature
UnknownMechano-redox control of integrin de-adhesion.
Not available
S-EPMC6054529 | biostudies-literature
UnknownQuercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain.
Not available
S-EPMC4583019 | biostudies-literature
UnknownAutoregulation of von Willebrand factor function by a disulfide bond switch.
Not available
S-EPMC5834005 | biostudies-literature
UnknownRapid prediction of acute thrombosis via nanoengineered immunosensors with unsupervised clustering for multiple circulating biomarkers.
Not available
S-EPMC11633740 | biostudies-literature
UnknownRapid Glass-Substrate Digital Light 3D Printing Enables Anatomically Accurate Stroke Patient-Specific Carotid Artery-on-Chips for Personalized Thrombosis Investigation.
Not available
S-EPMC12822522 | biostudies-literature
ProteomicsMechano-redox control of Mac-1 de-adhesion from ICAM-1 by protein disulfide isomerase promotes directional movement under flow
Quantification of the redox state of disulfide bonds in the beta 2 subunit of human recombinant Mac-1 integrin.
ORGANISM(S): Homo sapiens (Human) 
2023-04-09 | PXD032688 | Pride
Mac-1 Disulfide bonds Redox state 
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