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ProteomicsIndoxyl sulfate and p-cresyl sulfate directly promote vascular calcification via activation of inflammation and coagulation pathways
Vascular calcification contributes to high cardiovascular mortality in chronic kidney disease (CKD) patients. An association between the uremic toxins indoxyl sulfate (IS) and p-cresyl sulfate (PCS) and cardiovascular disease has been suggested. This study provides strong etiological evidence for in...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-06-13 | PXD012582 | Pride
Indoxyl sulfate Chronic kidney disease Vascular calcification Inflammation Hyperglycemia Coagulation P-cresyl sulfate Itraq-8plex 
TranscriptomicsSmall RNA sequencing in nine-day old nutrient-replete and N or P-limited wild type Arabidopsis seedlings
Identification of nutrient-specific microRNA expressed in Arabidopsis seedlings Small RNA sequencing of Arabidopsis wild type ecotype Columbia (Col-0) seedling under different nutrient limitation conditions
ORGANISM(S): Arabidopsis thaliana 
2011-04-20 | E-GEOD-28733 | biostudies-arrayexpress
ProteomicsA tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling
Pseudomonas aeruginosa is a difficult-to-treat Gram-negative bacterial pathogen causing life-threatening infections. Adaptive resistance (AR) to cationic peptide antibiotics such as polymyxin B impairs the therapeutic success. This self-protection is mediated by two component systems (TCS) consistin...
ORGANISM(S): Pseudomonas aeruginosa PAO1 Escherichia coli Bacillus subtilis 
2021-02-16 | PXD022426 | Pride
Response regulator P. aeruginosa Adaptive resistance Antimicrobial peptide Phosphorylation Activity-based protein profiling Parallel reaction monitoring Isotopically labeled tags B. subtilis 
Unknowntrans-Carbonyl-chloridobis(tri-p-tolyl-phosphine)rhodium(I) acetone solvate.
Not available
S-EPMC2960764 | biostudies-literature
TranscriptomicsEffects of single or 35 days oral exposure of adult Sprague-Dawley rats to p-tert-octylphenol on uterine gene expression
Contamination of the environment with endocrine disrupting chemicals (EDCs) has raised concerns about potential health hazards for humans and wildlife. P-tert-octylphenol (OP) is one such ubiquitous chemical reported to bind to the estrogen receptor (ER) and alter expression of estrogen-responsive g...
ORGANISM(S): Rattus norvegicus 
2009-02-20 | E-GEOD-14530 | biostudies-arrayexpress
ProteomicsA tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling
Pseudomonas aeruginosa is a difficult-to-treat Gram-negative bacterial pathogen causing life-threatening infections. Adaptive resistance (AR) to cationic peptide antibiotics such as polymyxin B impairs the therapeutic success. This self-protection is mediated by two component systems consisting of a...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 
PXD022470 | panorama
TranscriptomicsSingle-cell RNA-seq of Pdgfra+/Sca1+/Cd31- mouse cardiac cells
Adult mice hearts contain a population of resident mesenchymal stem cell (MSC)-like cells called cardiac colony forming units-fibroblast (cCFU-F). The cCFU-F are housed in a population of non-muscle cardiac cells that are Pdgfra+/Sca1+/Cd31- (S+P+ fraction). The goal of this experiment was to profil...
ORGANISM(S): Mus musculus 
2019-03-28 | E-MTAB-7365 | biostudies-arrayexpress
TranscriptomicsBarley root gene expression during colonisation by Piriformospora indica
The fungal mutualist Piriformospora indica is colonising barley roots thereby mediating various beneficial effects to its host. The interaction is characterised by an initial biotrophic interaction stage which is followed by a cell death-dependent colonisation phase. We used microarrays to identify ...
ORGANISM(S): Hordeum vulgare 
2010-05-19 | E-GEOD-13756 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human TK6 cells transduced with an oncoretrovirus expressing MDR1 (TK6MDR1) was vs untransduced TK6 cells and to TK6 cell transduced with an oncoretrovirus expressing the Neomycin resistance gene (TK6neo)
Gene expression of TK6 cells transduced with an oncoretrovirus expressing MDR1 (TK6MDR1) was compared to untransduced TK6 cells and to TK6 cell transduced with an oncoretrovirus expressing the Neomycin resistance gene (TK6neo). Two biological replicates of each were generated and the expression prof...
ORGANISM(S): Homo sapiens 
2005-09-15 | E-MEXP-428 | biostudies-arrayexpress
Transcriptomicscelecoxib-treated vs control breast tumours
Biopsies and surgical specimens were obtained from breast tumours treated and non-treated with celecoxib 400mg twice daily for 2 weeks
ORGANISM(S): Homo sapiens 
2013-03-28 | E-MTAB-566 | biostudies-arrayexpress
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