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MetabolomicsMicrobiome and metabolome patterns centered on cancer cachexia link skeletal muscle and adipose tissue depletion to clinical outcomes in locally advanced rectal cancer

This study employed untargeted serum metabolomics to delineate the specific metabolic landscape of cancer cachexia in patients with locally advanced rectal cancer. By analyzing LC-MS raw data from 133 patients (64 discovery, 69 validation), we identified and validated key cachexia-associated meta...

2026-05-09 | MTBLS13787 | MetaboLights
TranscriptomicsSample Matching by Inferred Agonal Stress in Gene Expression Analyses of the Brain
Gene expression patterns in the brain are strongly influenced by the severity of physiological stress at death. This agonal effect, if not well controlled, can lead to spurious findings in case-control comparisons. While many recent studies match samples by tissue pH and clinically recorded agonal...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-6306 | biostudies-arrayexpress
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (4)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022844 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (1)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022835 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (5)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD023000 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (3)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022839 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (2)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022837 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
UnknownQuantum-effective exact multiple patterns matching algorithms for biological sequences.
Not available
S-EPMC9138144 | biostudies-literature
TranscriptomicsMethylation profiling of lung squamous cell carcinomas vs surrounding normal tissue
Methylated genomic fragments from tumor and matching normal DNA were enriched with the methylated-CpG island recovery assay (MIRA); amplified, labeled and hybridized on Agilent CpG island tiling oligo arrays. Samples from tumor were labeled with Cy5 while the matching normal were labeled with Cy3 so...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-9622 | biostudies-arrayexpress
ProteomicsEnhanced feature matching in single-cell proteomics characterizes response to IFN-γ and reveals co-existence of different cell states- E.coli spike benchmark Proteomics experiment_Vendor Files
Proteome analysis by data-independent acquisition (DIA) has become a powerful approach to obtain deep proteome coverage, and has gained recent traction for label-free analysis of single cells. However, optimal experimental design for DIA-based single-cell proteomics has not been fully explored, and ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-22 | PXD053462 | Pride
E.coli Human 
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