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TranscriptomicsExpression profiling of Bmal mutant dorsal skin at telogen of hair follicle cycling
Hair follicles undergo recurrent cycling of controlled growth (anagen), regression (catagen), and relative quiescence (telogen) with a defined periodicity. Taking a genomics approach to study gene expression during synchronized mouse hair follicle cycling, we discovered that, in addition to circadia...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-14006 | biostudies-arrayexpress
TranscriptomicsExpression profiling of mouse dorsal skin during hair follicle cycling
Hair follicles undergo recurrent cycling of controlled growth (anagen), regression (catagen), and relative quiescence (telogen) with a defined periodicity. Taking a genomics approach to study gene expression during synchronized mouse hair follicle cycling, we discovered that, in addition to circadia...
ORGANISM(S): Mus musculus 
2009-07-17 | E-GEOD-11186 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Clock mutant dorsal skin at telogen
Hair follicles undergo recurrent cycling of controlled growth (anagen), regression (catagen), and relative quiescence (telogen) with a defined periodicity. Taking a genomics approach to study gene expression during synchronized mouse hair follicle cycling, we discovered that, in addition to circadia...
ORGANISM(S): Mus musculus 
2009-07-17 | E-GEOD-13579 | biostudies-arrayexpress
TranscriptomicsRNAseq of organ-cultured human hair follicles exposed to MEKi (Cobimetinib)
EGFR/MEK inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of hair follicle immune privilege and differential modulation of IL-33 and IL-37 expression. Our findings suggest that successful future management of EGFRi/MEKi-induced folliculitis requires r...
ORGANISM(S): Homo sapiens 
2024-07-19 | E-MTAB-13454 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse expressing human Cathepsin L inhibitor hurpin, skin alterations and increased carcinogenesis.
Aim of this study was to identify gene expression differences in the skin of hurpin (=headpin=serpinB13) transgenic mice in comparison to wildtype mice. Experiment Overall Design: Comparison of 4 transgenic mice with 3 wildtype mice. One wildtye sample was used two times. Experiment Overall Design:...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5236 | biostudies-arrayexpress
TranscriptomicsEffects of (-)-cannabidiol on human sebocytes
In the current study, we aimed at exploring the effects of the major non-psychotropic phytocannabinoid of Cannabis sativa, (-)-cannabidiol (CBD), on human sebaceous gland functions. We found that CBD behaved as a highly effective anti-acne agent, targeting all the three key, sebocyte-specific steps ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-57571 | biostudies-arrayexpress
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