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Hydrogenophaga sp. PBC Genome sequencing
Analyzing serological differences between AMA positive and negative PBC using DIGE
ORGANISM(S): Homo sapiens (Human) 
2014-11-27 | PXD001152 | Pride
Caspase-10 affects PBC pathogenesis
We performed a differential analysis of copy-number-alterations (CNAs) and mutations profiles by using pan-genomic array-CGH and next-generation-sequencing of 365 ‘cancer-associated’ genes, in a series of 14 pairs of matched primary breast cancer (PBC)/brain metastasis (BM) and assessed if the obser...
ORGANISM(S): Homo sapiens 
So far, high-efficiency and high-throughput analysis of C-terminal peptides is still full of challenges. In order to make the chemical derivatization-based strategies more practical and efficient, in this study we developed a new method, named 2-pyridinecarboxaldehyde (2PCA) and biotin labeling bas...
ORGANISM(S): Homo Sapiens 

A Genome-wide association study of primary biliary cirrhosis (PBC) with an Italian cohort and loci meeting suggestive criteria were confirmed using a replication dataset from a previous Canadian study. The results confirmed associations for IL12A, IL12RB2, and HLA (peak between DQA1 and DQB1) and...

Patients with head and neck squamous cell carcinoma (HNSCC) have a poor prognosis due to the development of locoregional recurrences, distant metastases and second primary tumors. There is an urgent need for biomarkers that enable detection and monitoring of the disease to provide adequate therapeut...
ORGANISM(S): Homo sapiens 
Profiles of Peripheral Blood MicroRNAs in Patients with Primary Biliary Cholangitis (PBC) and Healthy Controls
41K whole genome oligo-microarrays (Agilent Technologies) were used to characterize age-dependent changes in gene expression in peripheral blood cells (PBC) obtained from up to 8 individual NOD mice at 6 different time points (10 days (n=8), and 4 weeks (n=3), 8 weeks (n=7), 12 weeks (n=8), 16 weeks...
ORGANISM(S): Mus musculus 
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