Sort   by:  
 Page size 
TranscriptomicsRNA-seq of PBT2-Zn treated Fusobacterium nucleatum cells in vitro
To investigate the effect of the Zn ionophore, PBT2, on the transcriptomic response of Fusobacterium nucleatum ATCC 25586, RNA was extracted from bacterial samples which had been treated as follows: Untreated (0.006% DMSO v/v), DMSO-Zn treated (0.006% DMSO v/v + 200 uM ZnSO4), or PBT2-Zn treated (0....
ORGANISM(S): Fusobacterium nucleatum 
2021-07-15 | E-MTAB-8681 | biostudies-arrayexpress
ProteomicsQuantitative SWATH Proteomic Analysis of Campylobacter jejuni and Campylobacter coli Following Exposure to the Antimicrobial Ionophore PBT2
Campylobacter jejuni ATCC 33560 and Campylobacter coli ATCC BAA-1061 were exposed to the antimicrobial ionophore PBT2 to investigate proteome-wide responses associated with its antibacterial activity. Cultures were grown in Mueller-Hinton broth supplemented with 5% defibrinated horse blood and harve...
ORGANISM(S): Campylobacter jejuni subsp. jejuni ATCC 33560 Campylobacter coli RM2228 
2026-06-27 | PXD080115 | Pride
Campylobacter coli Ionophore Pbt2 Swath-ms Campylobacter jejuni 
GenomicsRNAseq transcriptome analysis of K. pneumoniae MS6671 with PBT2 and colistin
RNAseq transcriptome analysis of K. pneumoniae MS6671 with PBT2 and colistin
PRJNA643224 | ENA
GenomicsRNA-seq of PBT2-Zn treated Fusobacterium nucleatum cells in vitro
RNA-seq of PBT2-Zn treated Fusobacterium nucleatum cells in vitro
PRJEB36254 | ENA
UnknownNeurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria.
Not available
S-EPMC9027797 | biostudies-literature
TranscriptomicsRNAseq transcriptome analysis of K. pneumoniae MS6671 and E. coli MS8345 treated with PBT2
The emergence of colistin resistance in carbapenem-resistant and extended-spectrum ß-lactamase (ESBL)-producing bacteria is a significant threat to human health, and new treatment strategies are urgently required. Here we investigated the ability of the safe-for-human use ionophore PBT2 to restore a...
ORGANISM(S): Escherichia coli Klebsiella pneumoniae 
2019-06-13 | GSE132637 | GEO
GenomicsRNAseq transcriptome analysis of K. pneumoniae MS6671 and E. coli MS8345 treated with PBT2
RNAseq transcriptome analysis of K. pneumoniae MS6671 and E. coli MS8345 treated with PBT2
PRJNA548557 | ENA
UnknownChemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Not available
S-EPMC6299484 | biostudies-literature
GenomicsRNAseq transcriptome analysis of Streptococcus pneumoniae 23F treated with PBT2 and zinc
RNAseq transcriptome analysis of Streptococcus pneumoniae 23F treated with PBT2 and zinc
PRJNA673129 | ENA
TranscriptomicsRNAseq transcriptome analysis of K. pneumoniae MS6671 with PBT2 and colistin
The emergence of polymyxin resistance in carbapenem-resistant and extended-spectrum -lactamase (ESBL)-producing bacteria is a critical threat to human health, and new treatment strategies are urgently required. Here, we investigated the ability of the safe-for-human use ionophore PBT2 to restore an...
ORGANISM(S): Klebsiella pneumoniae 
2020-07-01 | GSE153553 | GEO
Sort   by:  
 Page size