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TranscriptomicsTranscription profiling of human B lymphocytes from Scott syndrome patient and daughter, treated with the A23187 calcium ionophore
B lymphoblast samples from control individual, Scott syndrome patient and Scott syndrome daughter. From each samples one part was treated with A23187 ca2+ ionophore. Treated and non-treated samples were then cultured further. Each sample was then processed in duplicate for hybridization on the micro...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1028 | biostudies-arrayexpress
TranscriptomicsRNA-seq of PBT2-Zn treated Fusobacterium nucleatum cells in vitro
To investigate the effect of the Zn ionophore, PBT2, on the transcriptomic response of Fusobacterium nucleatum ATCC 25586, RNA was extracted from bacterial samples which had been treated as follows: Untreated (0.006% DMSO v/v), DMSO-Zn treated (0.006% DMSO v/v + 200 uM ZnSO4), or PBT2-Zn treated (0....
ORGANISM(S): Fusobacterium nucleatum 
2021-07-15 | E-MTAB-8681 | biostudies-arrayexpress
ProteomicsIonophore 4-Br-A23187 causes copper stress in B. subtilis
Ionophores are small molecules or peptides that transport metal ions across biological membranes. Their transport capabilities are typically characterized in vitro using vesicles and single ion species. It is difficult to infer from these data which effects ionophores have on living cells in a compl...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2022-06-08 | PXD028938 | Pride
4-br-a23187 Antibiotic Ionophore Bacillus subtilis Copper 
ProteomicsProteomics explored the feasibility of curcumin as anticancer copper ionophore
As an essential micronutrient element in organisms, copper controls a host of fundamental cellular functions. Recently, copper-dependent cell growth and proliferation have been defined as "cuproplasia". Conversely, “cuproptosis” represents copper-dependent cell death, a nonapoptotic manner. So far, ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-17 | PXD037337 | Pride
Curcumin Curcumin 
GenomicsGenome-directed discovery of an octalin-containing polyether ionophore improves diabetic skin wound healing
Genome-directed discovery of an octalin-containing polyether ionophore improves diabetic skin wound healing
PRJNA1395366 | ENA
GenomicsRNAseq in PMA/Ca2+ ionophore stimulated HeLa cells transfected with negative control siRNA and siRNA against HNRNPU
RNAseq in PMA/Ca2+ ionophore stimulated HeLa cells transfected with negative control siRNA and siRNA against HNRNPU
PRJNA576700 | ENA
TranscriptomicsRNAseq in PMA/Ca2+ ionophore stimulated HeLa cells transfected with negative control siRNA and siRNA against HNRNPU
We sequenced mRNA from cultured HeLa cells transfected with control or HNRNPU siRNA to compare gene expression level in PMA/Ca2+ ionophore stimulated condition
ORGANISM(S): Homo sapiens 
2020-03-31 | GSE138668 | GEO
UnknownVoltammetric Mechanism of Multiion Detection with Thin Ionophore-Based Polymeric Membrane.
Not available
S-EPMC5029862 | biostudies-literature
ProteomicsQuantitative SWATH Proteomic Analysis of Campylobacter jejuni and Campylobacter coli Following Exposure to the Antimicrobial Ionophore PBT2
Campylobacter jejuni ATCC 33560 and Campylobacter coli ATCC BAA-1061 were exposed to the antimicrobial ionophore PBT2 to investigate proteome-wide responses associated with its antibacterial activity. Cultures were grown in Mueller-Hinton broth supplemented with 5% defibrinated horse blood and harve...
ORGANISM(S): Campylobacter jejuni subsp. jejuni ATCC 33560 Campylobacter coli RM2228 
2026-06-27 | PXD080115 | Pride
Campylobacter coli Ionophore Pbt2 Swath-ms Campylobacter jejuni 
UnknownIonophore Antibiotics Inhibit Type II Feline Coronavirus Proliferation In Vitro.
Not available
S-EPMC9415497 | biostudies-literature
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