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TranscriptomicsRNA-seq analysis of contextual fear conditioning
This dataset constitutes the first RNA-seq study of gene expression following contextual fear conditioning in the mouse hippocampus. 15 total samples were analyzed, including animals trained in a contexual conditioning paradigm (FC) and controls. Tissue was collected at 30 minutes (FC), as well as ...
ORGANISM(S): Mus musculus 
2015-07-22 | E-GEOD-63412 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression response upon infection with Toxoplasma gondii
The in vitro effect of infection with different strains of Toxoplasma gondii was tested 24 hours after infection of Human Foreskin Fibroblasts (HFF) The strains tested include RH, VEG, and transgenic strains of RH overexpressing ROP38 or ROP21 Total RNA of Toxoplasma gondii infected HFF cell was com...
ORGANISM(S): Homo sapiens 
2010-07-31 | E-GEOD-22402 | biostudies-arrayexpress
TranscriptomicsExpression data from sleep deprivation experiment in mouse hippocampus
We used microarrays to detail the global programme of gene expression underlying the effect of sleep deprivation in the mouse hippocampus and identified distinct classes of regulated genes during this process. Hippocampal tissue was taken from sleep deprived mice and time-matched non-sleep-deprived ...
ORGANISM(S): Mus musculus 
2012-09-06 | E-GEOD-33302 | biostudies-arrayexpress
TranscriptomicsContextual fear conditioning in the mouse hippocampus
A fundamental question in neuroscience is how memories are stored and retrieved in the brain. Many neurological, psychiatric and neurodevelopmental disorders are associated with cognitive deficits. Therefore characterizing the biological basis of these processes is critical for understanding normal ...
ORGANISM(S): Mus musculus 
2014-10-02 | E-GEOD-50423 | biostudies-arrayexpress
UnknownG6PD deficiency in Latin America: systematic review on prevalence and variants.
Not available
S-EPMC4156449 | biostudies-literature
TranscriptomicsClosely related parasites trigger distinct innate immune signaling pathways_II
The closely related protozoan parasites Toxoplasma gondii and Neospora caninum display similar life cycles, subcellular ultrastructure, invasion mechanisms, metabolic pathways, and genome organization, but differ in their host range and disease pathogenesis. Type II (γ) interferon has long been kn...
ORGANISM(S): Homo sapiens 
2013-03-29 | E-GEOD-45633 | biostudies-arrayexpress
TranscriptomicsGene expression linked to sleep homeostasis in murine cortex
Why we sleep is still one of the most perplexing mysteries in biology. Strong evidence, however, indicates that sleep is necessary for normal brain function and that the need to sleep is a tightly regulated process. Surprisingly molecular mechanisms that determine the need to sleep are incompletely ...
ORGANISM(S): Mus musculus 
2016-09-07 | E-GEOD-78215 | biostudies-arrayexpress
UnknownDifferences and contributors to global cognitive performance in the underrepresented Latinx Parkinson's disease population.
Not available
S-EPMC12766622 | biostudies-literature
UnknownMultiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes.
Not available
S-EPMC10483635 | biostudies-literature
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