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ProteomicsA Comparative Proteome and Phosphoproteome Reveal the Molecular Mechanism of the Difference between Imitative Wild Variety and Cultivated Variety of Dendrobium huoshanense C. Z. Tang et S. J. Cheng
This project intends to conduct comparative proteomics research on wild and cultivated varieties of Dendrobium huoshanense that are similar in plant shape and in the same growth and development stage through proteomics and protein modification omics combined with the differences in metabolites in De...
ORGANISM(S): Dendrobium huoshanense 
2022-06-24 | PXD022337 | Pride
Cultivated variety Proteome Dendrobium huoshanense Imitative wild variety Phosphoproteome 
UnknownMacrofocal multiple myeloma in the era of novel agents in China.
Not available
S-EPMC11783501 | biostudies-literature
ProteomicsDe-2-hydroxyisobutyrylation of clusterin attenuates neuropathology and memory deficits in an Alzheimer's disease mouse model
Backgroud Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder for which there is currently no cure, representing a serious clinical challenge. Lysine 2-hydroxyisobutyrylation (Khib) is a newly discovered post-translational modification that has been found to be wid...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-04 | PXD066261 | Pride
Clusterin Adeno-associated viruse 2-hydroxyisobutyrylation Post-translational modification Alzheimer's disease 
ProteomicsMouse lung proteomics and S-nitrosoproteomics using LC-MS/MS
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by excessive extracellular matrix deposition and impaired tissue repair. S-nitrosoglutathione reductase (GSNOR, encoded by ADH5) is a key enzyme that regulates protein S-nitrosylation by metabolizing S-nitrosoglutathione...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD061250 | Pride
Mouse Lung Lc-ms/ms 
ProteomicsQualitative Proteome-wide Analysis Reveal the Diverse Functions of Lysine Crotonylation in Dendrobium huoshanense C. Z. Tang et S. J. Cheng
Lysine crotonylation of histone proteins is a newly identified post-translational modification with diversified cellular functions. However, there’s few reports on lysine crotonylation of non-histone proteins in fruit plant cells. By using high-resolution LC-MS coupled with highly sensitive specific...
ORGANISM(S): Dendrobium huoshanense 
2021-11-29 | PXD028293 | Pride
Dendrobium huoshanense  lysine crotonylation  polysaccharide biosythesis 
ProteomicsGlobal PTM Mapping for Lysine 2-hydroxyisobutyrylation in one Oryza Sativa Japonica sample
By the combination of affinity enrichment and high-resolution LC-MS/MS analysis, large-scale lysine 2-hydroxyisobutyrlome analysis was performed in Oryza Sativa. Altogether, 9916 lysine 2-hydroxyisobutyrylation sites in 2512 protein groups were identified. Intensive bioinformatic analysis was then c...
ORGANISM(S): Oryza sativa (Rice) 
2018-10-26 | PXD005986 | Pride
Lysine 2-hydroxyisobutyrylation oryza sativa post-translational modification 
ProteomicsOryza sativa Lysine Acetylation LC-MS/MS
By the combination of affinity enrichment and high-resolution LC-MS/MS analysis, large-scale lysine acetylome analysis was performed in oryza sativa. Altogether, 1,003 lysine acetylation sites in 692 proteins were identified.
ORGANISM(S): Oryza sativa (Rice) 
2018-10-24 | PXD002773 | Pride
Oryza sativa Lysine acetylation Lc-ms/ms 
ProteomicsMS-based proteomics in HUVECs transfecting with IVT mRNA
The therapeutic success of in vitro-transcribed (IVT) mRNA depends on its stability and efficient translation. However, IVT mRNA is highly susceptible to immune-mediated degradation, limiting its efficacy. To investigate the binding protein profiles of IVT mRNA, we transfected HUVECs with 4SU-modifi...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD061961 | Pride
Lc-ms/ms Huvecs Ivt mrna 
UnknownGoat Milk Protein-Derived ACE Inhibitory Peptide SLPQ Exerts Hypertension Alleviation Effects Partially by Regulating the Inflammatory Stress of Endothelial Cells.
Not available
S-EPMC11545510 | biostudies-literature
UnknownObesity-Related Genetic Variants and Hyperuricemia Risk in Chinese Men.
Not available
S-EPMC6474097 | biostudies-literature
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