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In an endotoxaemic mouse model of sepsis, a tissue-based proteomics approach for biomarker discovery identified long pentraxin 3 (PTX3) as the lead candidate for inflamed myocardium. PTX3 accumulated as an octamer due to disulphide-bond formation in heart, kidney and lung ?common organ dysfunctions ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-10 | MSV000081708 | MassIVE
The study investigated the interaction between pentraxin-3 (PTX3), a soluble pattern-recognition receptor, and the fungal pathogen Aspergillus fumigatus. The aim was to identify the ligands for PTX3 and the impact of PTX3 on the immune response. A. fumigatus spores, hyphae or cell wall components we...
ORGANISM(S): Neosartorya fumigata (Aspergillus fumigatus) 
2024-08-02 | PXD043546 | Pride
In an endotoxaemic mouse model of sepsis, a tissue-based proteomics approach for biomarker discovery identified long pentraxin 3 (PTX3) as the lead candidate for inflamed myocardium. PTX3 accumulated as an octamer due to disulphide-bond formation in heart, kidney and lung ?common organ dysfunctions ...
ORGANISM(S): Mus musculus (Mouse) 
2014-07-01 | PXD001020 | Pride
Genomics
Pentraxin 3 (PTX-3) and severness of COVID
TLR4 deficiency attenuates kidney injury after ischemic reperfusion as measured by both renal function and morphology. To better understand the role of TLR4 during the acute kidney injury, we used DNA microarray to identify genes that were differentially expressed on kidneys in wildtype B10 mice and...
ORGANISM(S): Mus musculus 
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