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TranscriptomicsExpression data from Saccharomyces cerevisae strains overexpressing RNA-binding hnRNP Yra1
Transcription is a major obstacle for replication fork progression and a cause of genome instability. Such instability increases in mutants with an imbalance proportion of Yra1, a component of THO/TREX. We used microarrays to the global impact of Yra1 overexpression and found that no general impact ...
ORGANISM(S): Saccharomyces cerevisiae 
2016-03-11 | E-GEOD-68487 | biostudies-arrayexpress
TranscriptomicsChIP-chip data of HA-Yra1 and Rrm3-Flag in wild-type and cells overexpressing YRA1
Transcription is a major obstacle for replication fork progression and a cause of genome instability. Yra1 is an essential nuclear factor of the evolutionarily conserved family of hnRNP-like export factors that when overexpressed impairs mRNA export and cell growth. Through this ChIP-chip analysis i...
ORGANISM(S): Saccharomyces cerevisiae 
2016-03-11 | E-GEOD-68486 | biostudies-arrayexpress
TranscriptomicsPyrus communis: 'Ercolini' cultivar vs. 'Rocha' cultivar
Transcriptional profiling of pear tree comparing a resistant/tolerant cultivar with a susceptible cultivar to the Stemphylium vesicarium fungus Rocha' pear is an economically important portuguese Pyrus communis L. cultivar very susceptible to the Stemphylium vesicarium pathogenic fungus, the brown s...
ORGANISM(S): Pyrus communis 
2011-07-02 | E-GEOD-30353 | biostudies-arrayexpress
ProteomicsCells responding to bacterial pore-forming toxins release extracellular vesicles displaying similar proteomic content
The plasma membrane (PM) protects cells from extracellular threats and supports cellular homeostasis. Some pathogens produce pore-forming toxins (PFTs) that disrupt PM integrity by forming transmembrane pores. High PFT concentrations cause massive damage leading to cell death and facilitating infect...
ORGANISM(S): Homo sapiens (Human) 
2023-02-10 | PXD037166 | Pride
Calcium influx Shedding Extracellular vesicles Hela Listeriolysin o Label-free Pneumolysin Q exactive Pore-forming toxins Plasma membrane repair 
ProteomicsCx43-interaction network in the heart
The main objective of the present report was to unravel the Cx43-interaction network in the heart, and to establish the impact of heart ischemia and I/R upon these interactions. In order to characterize the cardiac Cx43 interactome under ischemia and I/R, a quantitative proteomic analysis was perfor...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-09 | PXD002331 | Pride
Connexin43  interactome  cardiomyocytes  ap-swath 
UnknownInternational Epidemiology of Carbapenemase-Producing Escherichia coli.
Not available
S-EPMC10444003 | biostudies-literature
TranscriptomicsTranscriptome analyses of dhh1 mutants in yeast
Previous experiments revealed that DHH1, a RNA helicase involved in the regulation of mRNA stability and translation, complemented the phenotype of a Saccharomyces cerevisiae mutant affected in the expression of genes coding for monocarboxylic-acids transporters, JEN1 and ADY2. In wild type cells, J...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-08 | E-GEOD-60983 | biostudies-arrayexpress
TranscriptomicsMycobacteria-induced anaemia: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2 but not hepcidin
Anaemia is a frequent complication of chronic infectious diseases but the exact mechanisms by which it develops remain to be clarified. In the present work, we used a mouse model of mycobacterial infection to study molecular alterations of iron metabolism. We show that four weeks after infection wit...
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-20024 | biostudies-arrayexpress
GenomicsEpigen-Brasil - samples
Epigen-Brasil samples using HumanOmni2.5
EGAD00010000787 | EGA
GenomicsGenomic Epidemiology of Complex Diseases in Population-based Brazilian Cohorts
The EPIGEN-Brasil Initiative is so far the largest Latin American initiative in population genomics and genetic epidemiology. Its main goal is to study the association between genetic variants found in the Brazilian population and complex diseases, taking into account one of the most important chara...
EGAS00001001245 | EGA
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