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ProteomicsHuman adipose insulin resistance
Adipocytes play a major role in whole body fuel homeostasis. Integrated proteomic analysis of adipose from insulin resistant versus healthy humans or mice or in 3T3-L1 adipocytes revealed defects in the mevalonate/coenzyme Q (CoQ) biosynthesis pathway as a unifying feature of adipocyte insulin resis...
ORGANISM(S): Homo sapiens (Human) 
2018-02-09 | PXD006891 | Pride
Human obese adipose tissue insulin resistance 
ProteomicsProteomic analysis of adipocyte insulin resistance
Insulin resistance is a major risk factor for human metabolic diseases including type 2 diabetes, cardiovascular diseases and some cancers. We analysed the proteome analyses across in vitro and in vivo models of insulin resistance to find common features of insulin resistance and identified lower e...
ORGANISM(S): Mus musculus (Mouse) 
2018-02-07 | PXD005128 | Pride
Insulin resistance Mouse Adipocyte Adipose tissue Orbitrap Lc-ms/ms 
UnknownThe transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes.
Not available
S-EPMC5789081 | biostudies-literature
UnknownKinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway.
Not available
S-EPMC4646237 | biostudies-literature
UnknownIntegrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass.
Not available
S-EPMC4863241 | biostudies-literature
UnknownA nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study.
Not available
S-EPMC7575021 | biostudies-literature
UnknownCross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity.
Not available
S-EPMC5516867 | biostudies-literature
UnknownSkeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans.
Not available
S-EPMC6585800 | biostudies-literature
UnknownInsulin signaling requires glucose to promote lipid anabolism in adipocytes.
Not available
S-EPMC7504926 | biostudies-literature
UnknownDynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.
Not available
S-EPMC7005519 | biostudies-literature
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