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TranscriptomicsDifferences in the genomic content of Bordetella pertussis strains before and after vaccine introduction in European countries
Resurgence of pertussis has been observed in many countries with high vaccination coverage and clonal expansion of certain Bordetella pertussis strains has been associated with recent epidemics in Europe. It is known that vaccinations have selected strains which are different from those used for vac...
ORGANISM(S): Bordetella pertussis 
2011-10-03 | E-GEOD-29579 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains
Comparative genome hybridization (CGH) of sample of 58 Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains selected to span four clusters as defined by MLST.
ORGANISM(S): Bordetella pertussis 
2005-12-31 | E-TABM-32 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of murine macrophages to the adenylate cyclase toxin of Bordetella pertussis
Three different recombinant forms of CyaA were used to investigate transcriptional responses of murine bone marrow-derived macrophages (BMDMs) using Affymetrix Mouse Genome Genechips. These forms were enzymically active, invasive CyaA, nonenzymically active, invasive CyaA (CyaA*) and non-enzymically...
ORGANISM(S): Mus musculus 
2013-09-22 | E-GEOD-51075 | biostudies-arrayexpress
ProteomicsPertussis toxin-catalyzed auto- and trans-ADP-ribosylation
This dataset was created to identify amino acids in pertussis toxin ADP-ribosyltransferase subunit (PtxS1) that get auto-modified during catalysis. In parallel, amino acids that get ADP-ribosylated by PtxS1 in the host cell target protein, G-protein inhibitory alpha subunit, were identified.
ORGANISM(S): Homo sapiens (Human) Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2025-05-06 | PXD050185 | Pride
Pertussis toxin Adp-ribosylation 
TranscriptomicsThe effect of pertussis toxin on lung airway gene expression during B. pertussis infection in mice
Genome-wide expression analysis of mouse lung responses to Bordetella pertussis infection and the effects of pertussis toxin Total lung RNA from wild-type and pertussis toxin-defficient B. pertussis-infected mice at two and four days post inoculation compared to control, mock-infected mice. Seven-w...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-33995 | biostudies-arrayexpress
ProteomicsIntegrating proteomic data with metabolic modelling provides insight into key pathways in Bordetella pertussis biofilms
Pertussis, commonly known as whooping cough is a severe respiratory disease caused by the bacterium, Bordetella pertussis. Despite widespread vaccination, pertussis resurgence has been observed globally. The development of the current acellular vaccine (ACV) has been based on planktonic studies. How...
ORGANISM(S): Bordetella pertussis 
2023-08-07 | PXD033664 | Pride
Lc-msms Lfq Bordetella pertussis Biofilm 
ProteomicsProteomic comparison of epidemic Australian Bordetella pertussis biofilm cells
Bordetella pertussis causes whooping cough, a severe respiratory disease. B. pertussis is a highly genetically homogenous species with only minor levels of genetic variation. It has been shown that single nucleotide polymorphism (SNP) cluster I containing the dominant pertussis toxin promoter allele...
ORGANISM(S): Bordetella pertussis 
2025-09-22 | PXD046513 | Pride
Tmt Bordetella pertussis Mrm-hr Biofilm Lc-ms/ms 
GenomicsBordetella pertussis
Bordetella pertussis antigen deficiency
PRJDB9628 | ENA
TranscriptomicsThe multifaceted RisA regulon of Bordetella pertussis
Bordetella pertussis, the etiological agent of whooping cough, regulates the expression of its virulence factors by the well-defined BvgA/S two-component regulatory system. Phosphorylated BvgA activates the virulence activated genes (vags) and represses via the activation of the bvgR gene the expres...
ORGANISM(S): Bordetella pertussis 
2016-08-20 | E-GEOD-77754 | biostudies-arrayexpress
GenomicsBordetella pertussis
Whole genome sequencing of Bordetella pertussis toxin negative, an opportunistic pathogen
PRJDB2414 | ENA
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