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Proteomics,MultiomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-02 | MSV000080878 | MassIVE
ProteomicsSNW1 is required for sister chromatid cohesion
Although splicing is essential for the expression of most eukaryotic genes, inactivation of splicing factors causes specific defects in mitosis. The molecular cause of this defect is unknown. Here we show that the spliceosome subunits SNW1 and PRPF8 are essential for sister chromatid cohesion in hum...
ORGANISM(S): Homo sapiens (Human) 
2016-06-29 | PXD001249 | Pride
Pre-mrna splicing Snw1 Mitosis Cell cycle Sister chromatid cohesion 
ProteomicsAbsolute quantification of cohesin and its regulators in human cells
The organisation of mammalian genomes into loops and topologically associated domains (TADs) regulates gene expression. The formation and maintenance of loops and TADs depends on the protein complex cohesin, which also holds replicated sister chromatids together from S phase until mitosis. To unders...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012712 | Pride
Fluorescence-correlation spectroscopy Mass spectrometry Cell cycle Genome organization Cohesin Sister chromatid cohesion 
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S-EPMC9857594 | biostudies-literature
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S-EPMC10326520 | biostudies-literature
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S-EPMC8491132 | biostudies-literature
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S-EPMC10600726 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
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S-EPMC9259496 | biostudies-literature
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