Sort   by:  
 Page size 
ProteomicsInteractome analysis of PHF2 using LC-MS combined with an immunoprecipitation assay
PHF2 demethylates lysine 9 in histone 3 and acts as a tumor suppressor. In liver pathogenesis, PHF2 has dual effects. PHF2 induces simple hepato-steatosis by epigenetically coactivating ChREBP. When lipid accumulation goes serious, it protects the liver from fibrogenesis by facilitating Nrf2 activit...
ORGANISM(S): Homo sapiens (Human) 
2023-10-18 | PXD044277 | Pride
Lc-msms Phf2 Hepatocellular carcinoma Hepg2 
ProteomicsThe epigenetic reader Phf2 is positioned in the genome by cohesin
Eukaryotic genomes are assembled into chromatin by histones and extruded into loops by cohesin. These mechanisms control important genomic functions, but whether histones and cohesin cooperate in genome regulation is poorly understood. Here we identify Phf2, a member of the Jumonji-C family of histo...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-18 | PXD057926 | Pride
Cohesin Genome regulation Phf2 Epigenetic reader 
ProteomicsPHF2-mediated H3K9me balance orchestrates heterochromatin stability and progenitor proliferation in early neurogenesisPHF2-mediated H3K9me balance orchestrates heterochromatin stability and progenitor proliferation in early neurogenesis
Heterochromatin stability is crucial for progenitor proliferation during early neurogenesis. It relays on the maintenance of local hubs of H3K9me. However, the current understanding of the processes involved in the formation of efficient localized levels of H3K9me remains limited. To address this in...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-11 | PXD051336 | Pride
Phf2 Dna damage Neural stem cells Heterochromatin integrity Histone demethylation 
GenomicsTranscriptome analysis in PHf2 KO C2C12 cells
Transcriptome analysis in PHf2 KO C2C12 cells
PRJNA940819 | ENA
GenomicsChIP-seq experiment of PHF2 and H3K9me2 in NSCs
ChIP-seq experiment of PHF2 and H3K9me2 in NSCs
PRJNA504430 | ENA
GenomicsHi-C in neural stem cells before and after Phf2 KO
Hi-C in neural stem cells before and after Phf2 KO
PRJNA1020089 | ENA
GenomicsThe epigenetic reader Phf2 is positioned in the genome by cohesin
The epigenetic reader Phf2 is positioned in the genome by cohesin
PRJNA1185173 | ENA
UnknownEpigenetic regulation of adipogenesis by PHF2 histone demethylase.
Not available
S-EPMC3636657 | biostudies-literature
UnknownPHF2 regulates sarcomeric gene transcription in myogenesis.
Not available
S-EPMC11068198 | biostudies-literature
GenomicsTranscriptome analysis in skeletal muscle conditional Phf2 KO gastrocnemius muscle in male mice
Transcriptome analysis in skeletal muscle conditional Phf2 KO gastrocnemius muscle in male mice
PRJNA1229496 | ENA
Sort   by:  
 Page size