Sort   by:  
 Page size 
MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
ProteomicsTandem affinity purification coupled with mass spectrometry (TAP-MS) to identify the proteins that interact with RAD51, RAD51 paralogs (RAD51B, RAD51C,RAD51D,XRCC2 and XRCC3), PFKP and PFKP-F649L in HeLa cells.
Tandem affinity purification coupled with mass spectrometry (TAP-MS) was used to identify the proteins that interact with RAD51,RAD51 paralogs (RAD51B, RAD51C,RAD51D,XRCC2 and XRCC3),PFKP and PFKP-F649L in HeLa cells. In addition, we also investigated the phosphorylation of RAD51.
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD070095 | Pride
Rad51paralogs Rad51 Pfkp-f649l Hela cells Rad51 phosphorylation Pfkp 
MetabolomicsFbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells
Not available
ORGANISM(S): Mus musculus 
ST001986 | MetabolomicsWorkbench
ProteomicsProteomic IP-MS analysis of Asprosin/PFKP in regulating cardiac hypertrophy model
This dataset contains two parts of proteomics data: a) the identification and analysis results of co-immunoprecipitation (Co-IP: Flag-asprosin/HA-PFKP) in cardiomyocytes overexpressing Flag-asprosin/HA-PFKP; b) the identification and analysis results of co-immunoprecipitation (Co-IP) using IgG as a ...
ORGANISM(S): Mus Musculus 
2025-12-24 | PXD072385 |
ProteomicsMouse embryonic stem cells LCMS-MS
We hypothesized that uncovering interactions between Pfkp and other proteins could help resolve the mechanism whereby Pfkp regulates germ layer differentiation. Towards this, Pfkp was immunoprecipitated from mESCs and mass spectrometry analysis used to identify a number of potential Pfkp-interacting...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-23 | PXD038944 | Pride
Lcms-ms Mouse Embryonic stem cells 
GenomicsGlycolytic Pfkp Acts as Lin41 Protein Kinase to Regulate Embryonic Stem Cell Differentiation
Glycolytic Pfkp Acts as Lin41 Protein Kinase to Regulate Embryonic Stem Cell Differentiation
PRJNA893540 | ENA
GenomicsEffect of PFKP deletion on gene expression in laryngeal carcinoma cells LIU-LSC-1
Effect of PFKP deletion on gene expression in laryngeal carcinoma cells LIU-LSC-1
PRJNA1043086 | ENA
TranscriptomicsGlycolytic Pfkp Acts as Lin41 Protein Kinase to Regulate Embryonic Stem Cell Differentiation
To investigate the synergistic role of Pfkp and Lin41 in the regulation of lineage differentiation, we knocked down Pfkp and Lin41 in mESC cells (R1 cells) by shRNAs respectively, and cultured for 6 days to form embryoid bodies (EBs).We then performed transcriptome sequencing of the Pfkp or Lin41 kn...
ORGANISM(S): Mus musculus 
2023-02-21 | GSE216394 | GEO
TranscriptomicsEffect of PFKP deletion on gene expression in laryngeal carcinoma cells LIU-LSC-1
To investigate the role of PFKP in laryngea cancer, we established a LIU-LSC-1 cell line with PFKP knocked down by lentivirus technique. We then performed gene expression profiling targeting the RNA-seq data of the control and PFKP knockdown groups.
ORGANISM(S): Homo sapiens 
2024-08-08 | GSE248242 | GEO
UnknownPFKP silencing suppresses tumor growth via the AXL-MET axis.
Not available
S-EPMC11628322 | biostudies-literature
Sort   by:  
 Page size