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ProteomicsDeciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach
Understanding how P4 signaling occurs in endometrial cells is important to guide the development of more effective therapeutic approaches to the numerous reproductive diseases caused by disrupted P4 signaling, resulting in subfertility or infertility (Bunch et al., 2013; Kim et al., 2013; Zhang and ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048494 | Pride
Proteomics Pgrmc2 Menstrual cycle Progesterone receptor Progesterone Decidualization Human endometrium Endometrial stromal cells Transcriptomics 
GenomicsPGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function
PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function
PRJNA512855 | ENA
UnknownPGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Not available
S-EPMC6895438 | biostudies-literature
TranscriptomicsPGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function
We describe a role for the poorly annotated protein PGRMC2 in retrograde transport of heme from mitochondria to the nucleus. In absence of PGRMC2, less signaling heme reaches the nucleus, with a consequent alteration of heme-sensitive transcriptional programs that ultimately engenders severe mitocho...
ORGANISM(S): Mus musculus 
2019-09-01 | GSE124621 | GEO
UnknownPGRMC2 is a pressure-volume regulator critical for myocardial responses to stress in mice.
Not available
S-EPMC11897200 | biostudies-literature
UnknownCloning, mapping and molecular characterization of porcine progesterone receptor membrane component 2 (PGRMC2) gene.
Not available
S-EPMC3036127 | biostudies-literature
UnknownAlterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosis.
Not available
S-EPMC3358041 | biostudies-literature
UnknownPGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface.
Not available
S-EPMC11344061 | biostudies-literature
GenomicsDeciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach
Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach
PRJNA1055541 | ENA
TranscriptomicsThe role of chorionic PGRMC2 and HLA-G in maintaining immune homeostasis at the chorio-decidual interface
The chorio-decidual interface (CDi) is formed by chorion trophoblasts (CTCs) and immune cell-rich decidua (DECs) cells. The roles of human leukocyte antigen (HLA)-G and progesterone receptor membrane component 2 (PGRMC2) in mediating innate immune homeostasis at this maternal-fetal interface interfa...
ORGANISM(S): Homo sapiens 
2024-01-02 | GSE251809 | GEO
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