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ProteomicsPhagoID: Quantitative in situ proximity labeling defines the proteomes of bead- and microbe-containing phagosome lumina across species, maturation, and immune activation
The phagosome is an immune organelle that integrates signals from diverse cargos to drive pathogen killing, tissue homeostasis, and antigen presentation. How this compartment coordinates such diverse functions remains incompletely understood. A comprehensive view of phagosomal composition across cel...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-10-02 | PXD055598 | Pride
Apex2 Turboid Proximity labeling Phagosome proteome Phagosomal proteome Hrp Phagosome lumen Phagosomal lumen Phagosome 
UnknownProximity labeling defines the phagosome lumen proteome of murine and primary human macrophages.
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S-EPMC11398489 | biostudies-literature
UnknownBetter Together: Current Insights Into Phagosome-Lysosome Fusion.
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S-EPMC7946854 | biostudies-literature
UnknownThe sodium proton exchanger NHE9 regulates phagosome maturation and bactericidal activity in macrophages.
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S-EPMC9293770 | biostudies-literature
UnknownIrregular particle morphology and membrane rupture facilitate ion gradients in the lumen of phagosomes.
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S-EPMC9680789 | biostudies-literature
UnknownMitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus.
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S-EPMC7323595 | biostudies-literature
UnknownCytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol.
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S-EPMC8688326 | biostudies-literature
UnknownRapid removal of phagosomal ferroportin in macrophages contributes to nutritional immunity.
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S-EPMC7839378 | biostudies-literature
UnknownPhagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB.
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S-EPMC5453720 | biostudies-literature
UnknownAutophagosomes fuse to phagosomes and facilitate the degradation of apoptotic cells in Caenorhabditis elegans.
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S-EPMC8769646 | biostudies-literature
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