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TranscriptomicsA genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina
Aging of biological systems is controlled by various processes which have a potential impact on gene expression. Here we report a genome-wide transcriptome analysis of the fungal aging model Podospora anserina. Total RNA of three individuals of defined age were pooled and analyzed by SuperSAGE (seri...
ORGANISM(S): Podospora anserina 
2013-12-20 | E-MTAB-2016 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Candida albicans cells of the wildtype strain SC5314 and a sky2 deletion mutant grown on different carbon sources (glucose, malic acid, succinic acid)
RNA-sequencing was performed to investigate the role of the Candida albicans protein kinase Sky2 in metabolic adaptation to alternative carbon sources. The Candida albicans wildtype strain SC5314 and a sky2 deletion mutant were grown in medium with either glucose (3h), malic acid (6h) or succinic ac...
ORGANISM(S): Candida albicans 
2026-04-01 | E-MTAB-16222 | biostudies-arrayexpress
ProteomicsProtective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection
The antiviral immune response to SARS-CoV-2 infection can limit viral spread and prevent development of pneumonic COVID-19. However, the protective immunological response associated with successful viral containment in the upper airways remain unclear. Here, we combine a multiomics approach with lon...
ORGANISM(S): Homo sapiens (Human) 
2022-01-17 | PXD030785 | Pride
Human Plasma Sars-cov-2 Proteomics Covid-19 
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:32:15:134-286 - samples
RNA sequencing data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002011 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-12-04-2016-13:35:10:904-287 - samples
ChIPseq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001002012 | EGA
GenomicsDATA_SET_marlboro-EEP-2013-03-15 - samples
WGBS data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
EGAD00001000366 | EGA
GenomicsWhole genome bisufite sequencing of smoking and non-smoking mother-child pairsBisufite sequencing, RNA-seq and ChIP-Seq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
Whole-blood samples of 16 mother-child pairs with differing maternal smoking behaviour were bisulfite treated and sequenced with deep coverage to identify smoking-associated differentially methylated regions. RNA-sequencing and ChIP-sequencing of 4 chromatin marks complete the data set and allow for...
EGAS00001000455 | EGA
ProteomicsProteome Profiling in Cerebrospinal Fluid Reveals Novel Biomarkers of Alzheimer’s Disease
Neurodegenerative diseases are a growing burden and there is an urgent need for better biomarkers for diagnosis, prognosis and treatment efficacy. Structural and functional brain alterations are reflected in the protein composition of cerebrospinal fluid (CSF). Alzheimer’s disease (AD) patients ha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-06 | MSV000088649 | MassIVE
ProteomicsEpigenetic silencing of tight junction protein CLDN10B in renal cancer including post-transplantation RCC and its endogenous reactivation by CRISPR results in cell growth suppression.
Background The kidney's tubular system, composed of nephrons and collecting ducts, relies on cellular planar polarity and tight junctions to maintain structure and function. Disruptions in this polarity contribute to diseases like cystic kidney disease and cancer. Tight junctions, such as those form...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-01 | MSV000095998 | MassIVE
ProteomicsThe HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues
The human leukocyte antigen (HLA) complex regulates the adaptive immune response by showcasing the intracellular and extracellular protein content to the immune system. T cells recognize these HLA-presented peptides as self or foreign and can elicit an immune response. In this work, we describe the...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096271 | MassIVE
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