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TranscriptomicsThe Heritage (HEalth, RIsk factors, exercise Training And GEnetics) family study
The overall objective of the heritage project is to study the role of the genotype in cardiovascular,metabolic and hormonal responses to aerobic exercise training and the contribution of regular exercise to changes in several cardiovascular disease and diabetes risk factors. The study cohort in this...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-47874 | biostudies-arrayexpress
TranscriptomicsImpact of resistance exercise on human skeletal muscle gene expression - ageing
The aim of this work was to produce a reproducible molecular signature of human muscle responses to resistance training and examine how such a profile relates to new and established exercise adaptation gene networks. Subjects were recruited from an age range of 18 to 75 y. Before beginning the study...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-47881 | biostudies-arrayexpress
UnknownEvidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Not available
S-EPMC3236649 | biostudies-literature
TranscriptomicsTranscription profiling by array of human BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension
Background: While BMPR2 mutation strongly predisposes to pulmonary arterial hypertension (PAH), only 20% of mutation carriers develop clinical disease. This finding suggests that modifier genes contribute to FPAH clinical expression. Since modifiers are likely to be common alleles, this problem is n...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-10767 | biostudies-arrayexpress
GenomicsNHLBI GO-ESP Family Studies: Pulmonary Arterial Hypertension

The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome (the "exome") that are associated with heart, lung and blood diseases. These and relat...

phs000354.v1.p1 | EGA
UnknownThe effects of palbociclib in combination with radiation in preclinical models of aggressive meningioma.
Not available
S-EPMC8325754 | biostudies-literature
UnknownAI-Techniques Loss-Based Algorithm for Severity Classification (ATLAS): a novel approach for continuous quantification of exertional symptoms during incremental exercise testing.
Not available
S-EPMC12758462 | biostudies-literature
UnknownExploring cytokine outputs for <i>ex vivo</i> diagnostics in drug reaction with eosinophilia and systemic symptoms (DRESS).
Not available
S-EPMC11665396 | biostudies-literature
UnknownHLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.
Not available
S-EPMC6612297 | biostudies-literature
UnknownEfficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial.
Not available
S-EPMC10352926 | biostudies-literature
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