Phophoproteomics

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Proteomics (5)

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Mus musculus (2)
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Acute myeloid leukemia (1)
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2025 (1)
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Lab affiliation

Breast Cancer Clinical Research Unit, CNIO, Spanish National Cancer Research Centre, Spain (1)
The Proteomics Facility of the University of Bergen (PROBE), The Department of Biomedicine, University of Bergen, Bergen, Norway (1)

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Phophoproteomics of PMA-stimulated neutrophils

Bone marrow murine neutrophils were stimulated with or without PMA to determine the phosphorylated proteins

ORGANISM(S): Mus Musculus

2025-10-28 | PXD069967 |

Phosphoproteomics reveals the disturb of kinase-substrates in intracerebral hemorrhage with hyperhomocysteinaemia

To elucidate the impact and mechanism of homocysteine on intracerebral hemorrhage at a system-wide level, we used a global phosphoproteomic approach combined with proteomics. Hyperhomocysteinaemia (HHcy) mice was induced by high methionine diet，and Experimental intracerebral hemorrhage was induced ...

ORGANISM(S): Mus Musculus

2023-01-31 | PXD039748 |

In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer

Triple-negative breast cancer (TNBC) lacks prognostic and predictive markers. We used high-throughput phosphoproteomics to build a functional TNBC taxonomy. A cluster of 159 phosphosites was upregulated in relapsed cases of a training set (n=34 patients). Eleven hyperactive kinases...

ORGANISM(S): Homo sapiens (Human)

2018-07-23 | PXD008012 | Pride

Quantitative proteomics and phosphoproteomics analyse the effect of ocnus on Drosophila spermatogenesis

For phophoproteomics, the nosGal4>w- (control) samples 1, 2, and 3 were labeled with iTRAQ tags 118, 119, and 121, respectively. Samples of nosGal4>ocn-hp 1, 2, and 3 were labeled with iTRAQ tags 115, 116, and 117, respectively. The labeled peptides were desalted and concentrated in Sep-Pack C18 Car...

ORGANISM(S): Drosophila Melanogaster

2022-08-13 | PXD036049 |

MS-based proteomic and phosphoproteomic characterization of the AML proteome

Acute myeloid leukemia (AML) is a hematological cancer that affects mainly the elderly. Although complete remission (CR) is achieved for the majority of the patients after induction and consolidation therapies, nearly two-thirds relapse within a short interval. Therefore, understanding of the biolog...