Phosphoenolpyruvate carboxykinase

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Unknown (523)
Transcriptomics (39)
Genomics (34)
Proteomics (18)
Metabolomics (7)
Models (3)

Organisms

Homo sapiens (11)
Mus musculus (8)
Glaesserella parasuis SH0165 (8)
Rhodobacter capsulatus (8)
Acromyrmex echinatior (8)
Streptomyces albidoflavus (8)
Bacillus subtilis subsp. subtilis str. 168 (5)
Corynebacterium glutamicum (3)
Drosophila melanogaster (3)
Drosophila mojavensis (2)
Aspergillus niger (2)
Podospora anserina (2)
Corynebacterium glutamicum ATCC 13032 (2)
Bacillus subtilis (2)
Corynebacterium glutamicum R (2)
Escherichia coli (1)
Saccharomyces cerevisiae (1)
Rattus norvegicus (1)
Aspergillus nidulans (1)
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Escherichia coli BL21(DE3) (1)
Komagataella pastoris (1)
Nakaseomyces glabratus (1)
Sinonovacula constricta (1)
Sparus aurata (1)
Mortierella alpina ATCC 32222 (1)
Edwardsiella piscicida EIB202 (1)
Fusarium graminearum PH-1 (1)
Gallus gallus (1)
Zea mays (1)

Organisms

Homo sapiens (5)
Mus musculus (5)
Corynebacterium glutamicum R (2)
Bacillus subtilis subsp. subtilis str. 168 (2)
Podospora anserina (1)
Drosophila mojavensis (1)
Corynebacterium glutamicum ATCC 13032 (1)
Sparus aurata (1)
Komagataella pastoris (1)
Nakaseomyces glabratus (1)
Sinonovacula constricta (1)
Escherichia coli BL21(DE3) (1)
Aspergillus niger (1)

Repository

ENA (31)
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Tissue

Conidium (1)
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Disease

Diabetes mellitus (2)
End stage renal disease (1)
Obesity (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (8)
Mass spectrometry assay (4)
Shotgun proteomics (4)
Mass spectrometry (3)
Data-dependent acquisition (2)
SWATH MS (2)
Gel-based experiment (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (3)
Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

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UNIPROT ID/AC

P10515 (2)
P01275 (2)
Q96G03 (2)
P54840 (2)
Q16822 (2)
Q15181 (2)
P17858 (2)
P35557 (2)
O75390 (2)
P11168 (2)
P16118 (2)
P05062 (2)
P00338 (2)
P07195 (2)
P09622 (2)
P07864 (2)
P04406 (2)
O00330 (2)
P30613 (2)
P36871 (2)
P06744 (2)
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P13929 (2)
O00757 (2)
P09467 (2)
P35575 (2)
P35558 (2)
Q16851 (2)
P00558 (2)

CHEBI ID

CHEBI:44897 (3)
CHEBI:15713 (3)
CHEBI:4170 (3)
CHEBI:4167 (3)
CHEBI:17659 (3)
CHEBI:30769 (3)
CHEBI:18066 (3)
CHEBI:15946 (3)
CHEBI:17552 (3)
CHEBI:32816 (3)
CHEBI:16908 (3)
CHEBI:16108 (3)
CHEBI:18357 (2)
CHEBI:16077 (2)
CHEBI:24636 (2)
CHEBI:15351 (2)
CHEBI:15377 (2)
CHEBI:422 (2)
CHEBI:30744 (2)
CHEBI:15346 (2)
CHEBI:28602 (2)
CHEBI:16526 (2)
CHEBI:28087 (2)
CHEBI:17835 (2)
CHEBI:17794 (2)
CHEBI:15996 (2)
CHEBI:16001 (2)
CHEBI:15846 (2)
CHEBI:29052 (2)
CHEBI:16905 (2)

Metabolite Name

Ingenol (3)
4-Hydroxycinnamic acid (3)
Lumichrome (3)
Taurine (3)
Labetalol (3)
Inosine (3)
Azelaic acid (3)
Creatinine (3)
Betaine (3)
Adenosine (3)
Choline (3)
Helicin (2)
Aspidocarpine (2)
Reserpic acid (2)
Madecassic acid (2)
Resibufogenin (2)
Xanthosine 5'-monophosphate (2)
Cromolyn (2)
Marrubiin (2)
Cyclopiazonic acid (2)
Disoxaril (2)
Arachidonoyl ethanolamide (2)
Steviol (2)
Nordihydroguaiaretic acid (2)
Triptophenolide (2)
Dicyclomine (2)
FFA(18:0) (2)
FFA(16:0) (2)
Cer(d18:1/18:0) (2)
Calcimycin (2)

First Public Date

2014 (9)
2026 (6)
2025 (5)
2024 (3)
2023 (2)
2016 (2)
2021 (1)
2019 (1)
2018 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (2)
Constraint-based model (1)

Lab affiliation

Forschungszentrum Juelich GmbH Institute of Bio- and Geosciences 1 Systems Biotechnology Group: Quantitative Microbial Phenotyping (1)
Dr. Aleksandra Skirycz Max-Planck-Institut für Molekulare Pflanzenphysiologie Potsdam Science Park Am Mühlenberg 1 14476 Potsdam (1)
Target Discovery Institute Nuffield Department of Medicine University of Oxford Roosevelt Drive Oxford OX3 FZ UK Tel: +44 (0) 1865 612 921 https://www.tdi.ox.ac.uk/research/research/tdi-mass-spectrometry-laboratory (1)
Anhui Province Key Laboratory of Crop Integrated Pest Management, School of Plant Protection, Anhui Agricultural University, Hefei 230036, China. (1)
Carnegie Institution at Stanford (1)
Synthetic Genetic Circuits, Department of Biology, Technical University Darmstadt, Darmstadt, Germany (1)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (1)
Department of Immunology, Microbiology and Parsitology Faculty of Science and Technology University of the Basque Country (UPV/EHU) (1)

IsPrivate

False (3)

Model Flag

Non Kinetic (2)

Submitter Keywords

FROG (1)

Classification

bacteria (4)
fungi (2)

Study type

Transcription profiling by array (15)
RNA-seq of coding RNA (2)
Unknown experiment type (1)
ChIP-chip by array (1)

Release Date

2023 (51)
2022 (44)
2019 (43)
2018 (41)
2025 (38)
2020 (38)
2021 (35)
2015 (33)
2024 (31)
2017 (30)
2014 (27)
2016 (21)
2011 (17)
2008 (17)
2010 (16)
2013 (12)
2012 (12)
2009 (9)
2026 (6)
2007 (5)
2006 (4)
2005 (3)
2000 (3)
2002 (2)
2004 (1)
1999 (1)
1995 (1)
1970 (1)

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Catabolite repression of phosphoenolpyruvate carboxykinase by a zinc finger protein under biotin- and pyruvate carboxylase-deficient conditions in Pichia pastoris

We have identified a methanol- and biotin-starvation-inducible zinc finger protein named ROP [repressor of phosphoenolpyruvate carboxykinase (PEPCK)] in the methylotrophic yeast Pichia pastoris. When P.pastoris strain GS115 (wild-type, WT) is cultured in biotin-deficient, glucose ammonium (Bio-) ...

ORGANISM(S): Pichia pastoris

2011-10-13 | E-GEOD-32948 | biostudies-arrayexpress

Complex regulation of the PEP carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum

DNA affinity chromatography with the promoter region of the Corynebacterium glutamicum pck gene, encoding phosphoenolpyruvate carboxykinase (PEPCk), led to the isolation of four transcriptional regulators, i.e., RamA, GntR1, GntR2 and IolR. Determination of the PEPCk activity of the deletion mutant...

ORGANISM(S): Corynebacterium glutamicum ATCC 13032

2013-07-29 | E-GEOD-44812 | biostudies-arrayexpress

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism

Neddylation is a post-translational mechanism that adds a ubiquitin-like protein, namely neural precursor cell expressed developmentally down-regulated protein 8, to target proteins, with yet-unknown consequences. Here we show in mice that neddylation in liver is modulated by nutrient availability. ...

ORGANISM(S): Mus musculus (Mouse)

2023-10-08 | PXD043054 | Pride

Glucose Metabolic Remodeling through Phosphoenolpyruvate Carboxykinase Isoform 2 Regulates Prostate Cancer Cell Tumorigenicity

Patients with aggressive prostate cancer generally present with poor outcomes. Identifying the factors regulating prostate cancer aggressiveness may open new avenues in therapy. Specifically, information from prostate cancer patient databases revealed that higher phosphoenolpyruvate carboxykinase is...

ORGANISM(S): Homo sapiens

2016-01-04 | E-GEOD-76470 | biostudies-arrayexpress

Effects of heterologous expression of phosphoenolpyruvate carboxykinase and phosphoenolpyruvate carboxylase on organic acid production in Aspergillus carbonarius.

Not available

S-EPMC4607725 | biostudies-literature

Kinetic and functional properties of human mitochondrial phosphoenolpyruvate carboxykinase.

Not available

S-EPMC5613351 | biostudies-literature

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism.

Not available

S-EPMC10487638 | biostudies-literature

Glucose Metabolic Remodeling through Phosphoenolpyruvate Carboxykinase Isoform 2 Regulates Prostate Cancer Cell Tumorigenicity