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UnknownPhosphopeptidome Profiling of Human Plasma for Hepatocellular Carcinoma Biomarker Discovery.
Not available
S-EPMC12831616 | biostudies-literature
UnknownIdentification of the PLK2-dependent phosphopeptidome by quantitative proteomics [corrected].
Not available
S-EPMC4206460 | biostudies-literature
TranscriptomicsRNA sequencing reveals that withaferin A reduces overexpression of Bruton's tyrosine kinase in glucocorticoid resistant multiple myeloma cells
Multiple myeloma (MM) is an incurable hematological malignancy characterized by the uncontrolled growth of plasma cells in the bone marrow. The major barrier in treating MM is the occurrence of primary and acquired therapy resistance to multiple existing anti-cancer drugs. Often, this therapy resist...
ORGANISM(S): Homo sapiens 
2021-03-31 | GSE162475 | GEO
UnknownCovalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells.
Not available
S-EPMC8037275 | biostudies-literature
UnknownPhosphocatalytic Kinome Activity Profiling of Apoptotic and Ferroptotic Agents in Multiple Myeloma Cells.
Not available
S-EPMC8657914 | biostudies-literature
ProteomicsHLA-I peptidomes and phosphopeptidomes (B*40, B*27, B*07, B*39)
As aberrant phosphorylation is a hallmark of tumor cells, the display of tumor-specific phosphopeptides by Human Leukocyte Antigen (HLA) class I molecules can be exploited in the treatment of cancer by T-cell-based immunotherapy. Yet, the characterization and prediction of HLA-I phospholigands is ch...
ORGANISM(S): Homo sapiens (Human) 
2016-12-12 | PXD005084 | Pride
Phosphopeptidome Mhc Peptidome Hla 
ProteomicsHLA-B40-peptidome - Increased Diversity of the HLA-B40 Ligandome by the Presentation of Peptides Phosphorylated at Their Main Anchor Residue
HLA class I molecules bind peptides derived from the intracellular degradation of endogenous proteins and present them to cytotoxic T lymphocytes, allowing the immune system to detect transformed or virally infected cells. It is known that endogenous HLA class I associated peptides may harbor posttr...
ORGANISM(S): Homo sapiens (Human) 
2014-02-03 | PXD000450 | Pride
Phosphopeptidome Hla Peptidome Mhc Hla-b40 
GenomicsRNA sequencing reveals that withaferin A reduces overexpression of Bruton's tyrosine kinase in glucocorticoid resistant multiple myeloma cells
RNA sequencing reveals that withaferin A reduces overexpression of Bruton's tyrosine kinase in glucocorticoid resistant multiple myeloma cells
PRJNA681920 | ENA
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