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Diaminoquinazolines represent a privileged scaffold for antimalarial discovery, including use as putative Plasmodium histone lysine methyltransferase inhibitors (BIX-01294). Despite this, robust evidence for their molecular targets, proteome-wide, is lacking. Here we report the design and developmen...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2018-02-16 | PXD008164 | Pride
The distribution of introduced photo-crosslinkable moieties onto a protein can affect a biomaterial’s crosslinking behavior, and therefore also the mechanical and biological properties. However, this information is also vital when developing biomaterials for tissue engineering and regenerative medic...
ORGANISM(S): Bos taurus (Bovine) 
2022-04-26 | PXD024622 | Pride
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