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ProteomicsBioID screening experiment to map proteins linked to PHYHD1
PHYHD1 is a 2-oxoglutarate-dependent dioxygenase. To shed light on the cellular function of human PHYHD1, we performed a BioID screening experiment to map proteins linked to PHYHD1 functionally. For that, we used HEK293T cells transiently expressing either BirA* or BirA*-tagged PHYHD1 in the absence...
ORGANISM(S): Homo sapiens (Human) 
2023-05-27 | PXD041792 | Pride
Hek293t Bioid Phyhd1 
GenomicsRNA-seq and Ribo-seq of PHYHD1-WT,PHYHD1△107-130（MT） and EV ccRCC cell line（7860）
RNA-seq and Ribo-seq of PHYHD1-WT,PHYHD1△107-130（MT） and EV ccRCC cell line（7860）
PRJNA1187475 | ENA
TranscriptomicsRNA-seq and Ribo-seq of PHYHD1-WT,PHYHD1△107-130（MT） and EV ccRCC cell line（7860）
We used RNA seq and Ribo-seq to evaluate the PHYHD1 gene expression changes among different groups (EV, MT, WT) to investigate the potential mechanisms by which PHYHD1 exerts its negative regulatory role in inhibiting excessive protein synthesis.
ORGANISM(S): Homo sapiens 
2025-03-03 | GSE282151 | GEO
UnknownA new role for PHYHD1 and related dioxygenases: demethylation of 2'-O-methylated nucleosides.
Not available
S-EPMC12709175 | biostudies-literature
TranscriptomicsGenes associated with the progression of neurofibrillary tangles in Alzheimer's disease
Transcriptome analysis of post-mortem brain tissue specimens from three brain regions (BRs), entorinal, temporal and frontal cortices, of 71 Japanese brain-donor subjects to identify genes relevant to the expansion of neurofibrillary tangles. In total, 213 brain tissue specimens (= 71 subjects × 3 B...
ORGANISM(S): Homo sapiens 
2019-05-24 | GSE131617 | GEO
UnknownGenes associated with the progression of neurofibrillary tangles in Alzheimer's disease.
Not available
S-EPMC4080317 | biostudies-literature
Unknownphytanoyl-CoA dioxygenase domain-containing protein 1 plays an important role in egg shell formation of silkworm (Bombyx mori).
Not available
S-EPMC8717975 | biostudies-literature
TranscriptomicsDifferentially expressed genes (DEGs) in oviducts of Yun7 and its giant egg mutant Yun7Ge of silkworm, Bombyx mori
Yun7Ge (Yun7Ge is represented by Ge in the high-throughput sequencing results) is a giant egg mutant found in the silkworm variety Yun7 (Yun7 is represented by Se in the high-throughput sequencing results). The amount of laid eggs and the hatching rate of Yun7Ge are reduced, which is not conducive t...
ORGANISM(S): Bombyx mori 
2021-05-01 | GSE173672 | GEO
UnknownIdentification of key genes in invasive clinically non-functioning pituitary adenoma by integrating analysis of DNA methylation and mRNA expression profiles.
Not available
S-EPMC6892283 | biostudies-literature
GenomicsGenes associated with the progression of neurofibrillary tangles in Alzheimer's disease
Genes associated with the progression of neurofibrillary tangles in Alzheimer's disease
PRJNA544416 | ENA
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