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MetabolomicsIntegrated multi-omics analysis and experimental verification reveal the involvement of the PI3K/Akt signaling pathway in myometrial fibrosis of adenomyosis.

This analysis established comprehensive metabolomic profiles of adenomyosis patients and revealed widespread alterations in the metabolome within normal and fibrotic myometrium. Integrated analysis shown significant associations between metabolomic data and fibrosis . This study is the first to d...

2025-05-12 | MTBLS11965 | MetaboLights
ProteomicsResearch on the secretome of Arabidopsis PHR1 in Pi-starvation response
Through hydroponic culture under phosphate-sufficient (+Pi) and phosphate-deficient (−Pi) conditions, a total of 2,078 high-confidence secreted proteins were quantitatively identified from WT and phr1 plants. These proteins were functionally categorized into phosphatases, signal transduction protein...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-10-05 | PXD081553 | Pride
Phr1 I.e. arabidopsis thaliana Pi-starvation response Lc-msms 
UnknownPotential inhibitory effects of compounds ZK-PI-5 and ZK-PI-9 on trehalose and chitin metabolism in Spodoptera frugiperda (J. E. Smith).
Not available
S-EPMC10090375 | biostudies-literature
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
UnknownElucidating π-π interaction-induced extension effect in sandwich phthalocyaninato compounds.
Not available
S-EPMC9092954 | biostudies-literature
ProteomicsSoybean, root-rhizobia, LC-MSMS
We previously found that rhizobia-inoculation enhanced the soybean's salt tolerance; the transcription factor (TF) GmMYB173 and its downstream gene GmCHS5 dictate soybean’s flavonoid metabolism in response to this stress. For revealing the mechanism of the enhancement, quantitative phosphoproteomics...
ORGANISM(S): Glycine max 
2019-09-02 | PXD006600 | Pride
Lc-msms Root-rhizobia Soybean 
ProteomicsSoybean, Root, LC-MSMS - Mechanisms of soybean roots' tolerances to salinity revealed by proteomic and phosphoproteomic comparisons between two cultivars
In the current study, we compared phosphoproteomic and proteomic changes in roots of different soybean seedlings of a salt-tolerant cultivar (Wenfeng07) and a salt-sensitive cultivar (Union85140) induced by salt stress. The root samples of Wenfeng07 and Union85140 at three-trifoliate stage were coll...
ORGANISM(S): Glycine soja (Wild soybean) 
2015-10-01 | PXD002856 | Pride
Lc-msms Salinity stress Soybean Root 
UnknownOne AP2/ERF Transcription Factor Positively Regulates Pi Uptake and Drought Tolerance in Poplar.
Not available
S-EPMC9099566 | biostudies-literature
UnknownPI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail.
Not available
S-EPMC4749301 | biostudies-literature
UnknownConformationally dynamic π-conjugation: probing structure-property relationships of fluorescent tris(N-salicylideneaniline)s.
Not available
S-EPMC3224823 | biostudies-literature
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