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TranscriptomicsPeturbation of PICALM Levels Alters Cellular Cholesterol Metabolism
PICALM (Phosphatidyl Inositol Clathrin Assembly Lymphoid Myeloid protein) is a ubiquitously expressed protein that plays a role in clathrin-mediated endocytosis. PICALM also affects the internalization of SNAREs and modulates macroautophagy. Chromosomal translocations that result in the fusion of PI...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-64855 | biostudies-arrayexpress
TranscriptomicsPeturbation of PICALM Levels Alters Cellular Cholesterol Metabolism
PICALM (Phosphatidyl Inositol Clathrin Assembly Lymphoid Myeloid protein) is a ubiquitously expressed protein that plays a role in clathrin-mediated endocytosis. PICALM also affects the internalization of SNAREs and modulates macroautophagy. Chromosomal translocations that result in the fusion of PI...
ORGANISM(S): Mus musculus 
2015-06-17 | GSE64855 | GEO
ProteomicsProteomic studies of human placentas reveal partnerships associated with preeclampsia, diabetes, gravidity, and labor
VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of chorionic villi at term revealed its partners MDMX (Double minute 4 protein) and PICALM (Phosphatidylinositol-binding clathrin assembly protein). Subsequently,...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD050049 | Pride
Vegfr2 Placenta Hofbauer cells Mdmx Trim21 Picalm Oxytocin receptor Proteomics 
UnknownAn intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform.
Not available
S-EPMC4150683 | biostudies-literature
TranscriptomicsEZH2 mutations can be detected in 23% of PICALM-MLLT10 (CALM-AF10) positive acute leukemias
Interest focuses on genes encoding histone demethylases in hematologic malignancies, such as EZH2 (enhancer of zeste homolog 2). EZH2 mutations were recurrently observed in lymphomas and chronic myeloid malignancies, but data in acute leukemias are limited. We investigated 13 PICALM-MLLT10 (=CALM-AF...
ORGANISM(S): Homo sapiens 
2011-11-25 | GSE30599 | GEO
GenomicsMus musculus
Peturbation of PICALM Levels Alters Cellular Cholesterol Metabolism
PRJNA272401 | ENA
UnknownGenetics of PICALM expression and Alzheimer's disease.
Not available
S-EPMC3949918 | biostudies-literature
UnknownModulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.
Not available
S-EPMC4467867 | biostudies-literature
TranscriptomicsEZH2 mutations can be detected in 23% of PICALM-MLLT10 (CALM-AF10) positive acute leukemias
Interest focuses on genes encoding histone demethylases in hematologic malignancies, such as EZH2 (enhancer of zeste homolog 2). EZH2 mutations were recurrently observed in lymphomas and chronic myeloid malignancies, but data in acute leukemias are limited. We investigated 13 PICALM-MLLT10 (=CALM-AF...
ORGANISM(S): Homo sapiens 
2011-11-25 | E-GEOD-30599 | biostudies-arrayexpress
UnknownPICALM and Alzheimer's Disease: An Update and Perspectives.
Not available
S-EPMC9776874 | biostudies-literature
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