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ProteomicsVEGFR N-glycosylation
Vascular endothelial growth factor receptor-2 (VEGFR2) is a highly N-glycosylated receptor tyrosine kinase involved in pro-angiogenic signaling in physiological and pathological contexts, including cancer. VEGFR2 post-translational modifications (PTMs) and their roles in receptor function and signal...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-08 | PXD012629 | Pride
Vegfr2 Rtk N-glycosylation Nlc-ms/ms Mouse Glycopeptides 
TranscriptomicsThe miR-126/VEGFR2 axis controls the innate response to pathogen-associated nucleic acids
microRNA-126 is a microRNA predominately expressed by endothelial cells and controls angiogenesis. Unexpectedly, we found that mice deficient in miR-126 have a major impairment in their innate response to pathogen-associated nucleic acids, as well as HIV, which results in more widespread cell infect...
ORGANISM(S): Mus musculus 
2013-11-24 | E-GEOD-51255 | biostudies-arrayexpress
TranscriptomicsVEGFR2 Y949F (lung RNAseq - mice)
RNA sequencing of lung tissue from transgenic mice in order to investigate the effect of a single tyrosine to phenylalanine exchange in the endothelial receptor VEGFR2 at position Y949. This exchange creates a mouse with unleaky blood vessels which is an advantage in several diseases such as cancer ...
ORGANISM(S): Mus musculus 
2020-06-12 | E-MTAB-9163 | biostudies-arrayexpress
GenomicsVEGFR2
VEGFR2 Y949F mutation
PRJEB47233 | ENA
GenomicsVEGFR2
VEGFR2 Y949F mutation
PRJEB44298 | ENA
ProteomicsVEGFR2 pY1173 binding partners as identified by shotgun proteomics
The main goal of the project was to identify proteins binding to vascular endothelial growth factor receptor 2 (VEGFR2) phosphorylation site Y1173. Synthetic peptides, phosphorylated or not, covering different tyrosine phosphorylation sites in VEGFR2 were immobilized and incubated with cell lysates ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-19 | PXD041024 | Pride
Sh2 domain-binding Lc-ms Vegf Vegfr2 py1173 
GenomicsVEGFR2 Y949F (lung RNAseq - mice)
VEGFR2 Y949F (lung RNAseq - mice)
PRJEB38638 | ENA
ProteomicsGLUTAMINE METABOLISM VIA TRANSAMINATION REGULATES VEGFR2 TRANSLATION DURING ANGIOGENESIS
Angiogenesis, the formation of new blood vessels from pre-existing ones, is a complex and demanding biological process that plays an important role in physiological as well as pathological settings such as cancer and ischemia. Given its critical role, the regulation of endothelial growth factor rece...
ORGANISM(S): Homo sapiens (Human) 
2022-04-22 | PXD022379 | Pride
Human Angiogenesis Glutamine Vegfr2 
ProteomicsProteomic studies of human placentas reveal partnerships associated with preeclampsia, diabetes, gravidity, and labor
VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of chorionic villi at term revealed its partners MDMX (Double minute 4 protein) and PICALM (Phosphatidylinositol-binding clathrin assembly protein). Subsequently,...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD050049 | Pride
Vegfr2 Placenta Hofbauer cells Mdmx Trim21 Picalm Oxytocin receptor Proteomics 
GenomicsTumor-independent host gene expression changes induced by VEGFR2 antibody
Tumor-independent host gene expression changes induced by VEGFR2 antibody
PRJNA446646 | ENA
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