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ProteomicsVEGF orchestration of the p130Cas Interactome
p130Cas is a polyvalent adapter protein essential for cardiovascular development, and with a key role in cell movement. In order to identify the pathways by which p130Cas exerts its biological functions in endothelial cells we mapped the p130Cas interactome and its dynamic changes in response to VEG...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080860 | MassIVE
TranscriptomicsTranscription profiling of human umbilical vein endothelial cells (HUVEC) treated with VEGF-A
Angiogenesis, the formation of new capillaries by sprouting from preexisting vessels, is mainly induced by VEGF-A. To identify genes which are induced by VEGF-A in endothelial cells, HUVEC were starved and induced by VEGF-A165 for 30, 60 and 150min. RNA of induced and uninduced cells was isolated an...
ORGANISM(S): Homo sapiens 
2009-10-20 | E-GEOD-15464 | biostudies-arrayexpress
ProteomicsKT01: The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis
ORGANISM(S): Bartonella Henselae Str. Houston-1 
2020-06-10 | PXD017507 | JPOST Repository
ProteomicsKT01_b: The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis. Wild type.
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis. Wild type.
ORGANISM(S): Bartonella Henselae Str. Houston-1 
2020-06-10 | PXD018354 | JPOST Repository
TranscriptomicsFGF-dependent regulation of VEGF signaling via transcriptional control of VEGF receptor 2 expression
Numerous studies have suggested a link between fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) signaling pathways; however the nature of this link has not been established. To evaluate this relationship we investigated VEGF signaling in endothelial cells with disrupted F...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-28483 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing to identify transcription factor regulatory network and alternative splicing in endothelial cells under VEGF stimulation
Human umbilical vein vascular endothelial cells (HUVECs) are crucial for angiogenesis that benefits functional recovery after cerebral infarction. This study aims to investigate the mechanisms underlying the effects of vascular endothelial growth factor (VEGF) on HUVECs. HUVECs were treated with 16 ...
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-71216 | biostudies-arrayexpress
GenomicsControl of VEGF-A trancriptional programs by pausing and genomic compartmentalization
Vascular endothelial growth factor A (VEGF-A) is a master regulator of vascular development and function. Consequently, VEGF-A regulated gene expression programs have been under heavy research. In this study we study the transcriptional regulation of VEGF-A-responsive genes in primary aortic endothe...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-52642 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat aortic rings treated with angiopoietin-1, VEGF or untreated
Specific Aims ; To identify novel transcriptional events associated with angiogenesis in VEGF and Ang-1 stimulated rat aortic rings. Our studies take advantage of the capacity of rat aortic rings to generate new vessels in collagen gels. Rat aortic rings embedded in collagen gel immediately after e...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-3355 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression in HMVECs: control vs. VEGF-treated vs. PEDF/VEGF-treated
MicroRNA expression profiling of human microvascular endothelial cells (HMVECs) treated with either vascular endothelial growth factor (VEGF) only or in combination with the natural angiogenesis inhibitor pigment epithelial-derived factor (PEDF). Originally we were interested in the microRNA-mediat...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-34735 | biostudies-arrayexpress
TranscriptomicsA compact VEGF signature associated with distant metastases and poor outcomes
Results When compared with each other, primary tumors and regional metastases showed statistically indistinguishable gene expression patterns. Supervised analyses comparing patients with distant metastases versus primary tumors or regional metastases showed that the distant metastases were distinct...
ORGANISM(S): Homo sapiens 
2009-03-31 | E-GEOD-3521 | biostudies-arrayexpress
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