Sort   by:  
 Page size 
ProteomicsTotal proteome analysis of WT vs TRAP1 KO in HCT-116 and HEK-293T cells grown on different carbon sources.
The molecular chaperone TRAP1, the mitochondrial isoform of cytosolic HSP90, remains poorly understood with respect to its pivotal role in the regulation of mitochondrial metabolism. To characterize the impact of TRAP1 in maintaining the cellular proteome under different energy sources we carried ou...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015828 | Pride
Oxidative phosphorylation Trap1 Mitochondrion Hsp90 Molecular chaperone 
UnknownQuantitative analysis of commensal Escherichia coli populations reveals host-specific enterotypes at the intra-species level.
Not available
S-EPMC4554456 | biostudies-literature
UnknownSimple Imaging System for Label-Free Identification of Bacterial Pathogens in Resource-Limited Settings.
Not available
S-EPMC11599477 | biostudies-literature
UnknownHuman aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.
Not available
S-EPMC6691995 | biostudies-literature
TranscriptomicsSexual cell fate reprogramming in the ovary by DMRT1
Transcription factors related to the insect sex determination gene Doublesex (DMRT proteins) control sex determination and/or sexual differentiation in diverse metazoans. They also are implicated in transitions between sex-determining mechanisms during vertebrate evolution. In mice Dmrt1 is required...
ORGANISM(S): Mus musculus 
2015-02-27 | E-GEOD-64960 | biostudies-arrayexpress
TranscriptomicsThe acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
It is well known that both recipient cells and donor nuclei demonstrate a mitotic advantage as observed in the traditional reprogramming with somatic cell nuclear transfer (SCNT). However, It is not known whether a specific mitotic factor plays a critical role in reprogramming. Here we identify an i...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-66798 | biostudies-arrayexpress
TranscriptomicsMassive sequencing of hybrid DNA obtained by DNA:RNA immunoprecipitation (DRIP) in extracellular microvesicles (MV) produced by HeLa cells (using S9.6 antibody)
Hybrid (Bound) and non-hybrid (Unbound) DNA from Hela EV was isolated using DRIP procedure as follows. Between 1-5μg of nucleic acid DNA from EVs (DNase0 treated) was incubated overnight with 1μg of anti-DNA-RNA Hybrid (S9.6) antibody (KeraFast) under rotation at 4°C in 500μl of binding buffer (10mM...
ORGANISM(S): Homo sapiens 
2023-03-30 | E-MTAB-9634 | biostudies-arrayexpress
GenomicsIL-10 production and metabolic regulation in macrophages are linked by a TLR-driven CREB-mediated mechanism
IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections macrophages are an important source of IL-10, however the molecular mechanism underpinning production of IL-10 by these cells is poorly characterized. Here, bone ...
ORGANISM(S): Mus musculus 
2015-07-08 | E-GEOD-64844 | biostudies-arrayexpress
GenomicsERa and PolII ChIP seq from KIKO mouse uterus
ChIP-seq from mice with DNA binding mutations in Esr1 (KIKO mouse). Estrogen Receptor M-NM-1 (ERM-NM-1) interacts with DNA, directly, or indirectly via other transcription factors, referred to as M-bM-^@M-^\tetheringM-bM-^@M-^]. Evidence for tethering is based on in vitro studies and a widely used M...
ORGANISM(S): Mus musculus 
2014-04-03 | E-GEOD-56466 | biostudies-arrayexpress
GenomicsEpigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
Two-thirds of gene promoters in mammals are associated with regions of non-methylated DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation. In lower vertebrates, computational CGI predictions often reside away from gene promoters, suggesting a major divergence i...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2013-01-22 | E-GEOD-43512 | biostudies-arrayexpress
Sort   by:  
 Page size