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TranscriptomicsArray-based comparative genomic hybridization analysis of primary neuroblastoma
We conducted microarray-based comparative genomic hybridization (array-CGH) with a DNA chip carrying 2,464 BAC clones to examine genomic aberrations of 236 neuroblastomas (112 sporadic and 124 mass screening-detected). In paralell, gene-expression profiling was also performed by using in-house cDNA ...
ORGANISM(S): Homo sapiens 
2007-08-06 | E-GEOD-5784 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 panel
Array comparative genomic hybridization characterization and comparison of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 panel.
ORGANISM(S): Homo sapiens 
2005-11-23 | E-TABM-65 | biostudies-arrayexpress
TranscriptomicsGenome position and gene amplification - expressional profiling of methotrexate resistant colonies
We investigated the influence of genome position on propensity to amplify. First, we integrated a mutant form of DHFR into different positions in the human genome, challenged cells with methotrexate and then studied the genomic alterations arising in drug resistant cells. We observed site specific d...
ORGANISM(S): Homo sapiens 
2007-10-08 | E-GEOD-6361 | biostudies-arrayexpress
TranscriptomicsDistinct Sets of Genetic Alterations in Melanoma
We compared genome-wide DNA copy number alterations and mutational status in BRAF and RAS genes of 126 primary melanomas arising in four groups in which UV exposure differ: skin with (n=30), and without chronic sun damage (n=40); palms, soles and subungual (acral) sites (n=36) (which have very littl...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2631 | biostudies-arrayexpress
TranscriptomicsDNA profiling of serous ovarian and Fallopian tube carcinomas with array CGH and MLPA
Primary serous ovarian carcinoma (OVCA) and serous Fallopian tube carcinoma (FTC), both belonging to the BRCA-linked tumour spectrum, share many properties and are treated similarly. However, a detailed molecular comparison has been lacking. We hypothesized that comparative genomic studies of serous...
ORGANISM(S): Homo sapiens 
2008-07-08 | E-GEOD-12040 | biostudies-arrayexpress
UnknownpRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia.
Not available
S-EPMC340938 | biostudies-literature
UnknownA large field CCD system for quantitative imaging of microarrays.
Not available
S-EPMC1456328 | biostudies-literature
TranscriptomicsCo-amplification at 8p and 11q in breast tumors and cell lines with 8p11q array Genomic Comparative Hybridization
Co-amplification at chromosomes 8p11-8p12 and 11q12-11q14 occurs often in breast tumors, suggesting possible cooperation between genes in these regions in oncogenesis. We used high resolution array comparative genomic hybridization (array CGH) to map the minimal amplified regions. The 8p and 11q a...
ORGANISM(S): Homo sapiens 
2009-09-02 | E-GEOD-12761 | biostudies-arrayexpress
UnknownIsolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer.
Not available
S-EPMC3395839 | biostudies-literature
UnknownGenome position and gene amplification.
Not available
S-EPMC2394771 | biostudies-literature
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