Sort   by:  
 Page size 
ProteomicsIdentification of the Saccharomyces cerevisiae ZMP binders
5′-phosphoribosyl-5-amino-4-imidazole carboxamide monophosphate (ZMP) is a metabolic intermediate of the de novo purine biosynthesis pathway. Its accumulation in several cell types from bacteria to human is associated with growth impairment. Identification of ZMP-binding proteins was performed to un...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-21 | PXD007780 | Pride
Purines Affinity chromatography Yeast 
ProteomicsEffect of acadesine and overexpression of the karyopherin Kap123 on nuclear abundance of yeast proteins
Based on genetic and affinity chromatography experiments, the karyopherin Kap123 was identified as an important player in the cellular response to the drug acadesine (AICAR, 5′-phosphoribosyl-5-amino-4-imidazole carboxamide). Since Kap123 mediates nuclear import of multiple proteins we hypothesized ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-23 | PXD007779 | Pride
Karyopherin Yeast Nucleus Aicar 
TranscriptomicsEffect of 5-amino-4-imidazolecarboxamide ribotide (AICAr) supplementation on global transcription
We investigated the effects of AICAr supplementation on the global transcriptome of Y2950. The Y2950 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29019 | biostudies-arrayexpress
TranscriptomicsRole of Ado1p in the transcriptional response associated with AICAr supplementation
We investigated the role of Ado1p associated with AICAr supplementation on the global transcriptome of Y3188. The Y3188 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29020 | biostudies-arrayexpress
TranscriptomicsEffect of AICAr and SAICAr accumulation on global transcription in the ade3 mutant
We investigated the effects of AICAr and SAICAr accumulation on the global transcriptome of yeast, comparing the ade3 mutant to the WT strain. The ade3 mutant strain (Y4143) was compared to the WT strain (Y2946). For each comparison, we made 2 technical replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29021 | biostudies-arrayexpress
TranscriptomicsTye7 regulates yeast Ty1 retrotransposon sense and antisense transcription in response to adenylic nucleotides stress
We investigated the effects of adenine starvation on the global yeast transcriptome. In this work, global transcription analyses were combined with measurements of intracellular nucleotides pools by HPLC. The bas1delta strain grown with or without adenine was compared to the WT strain grown with or ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-10 | E-GEOD-28579 | biostudies-arrayexpress
Sort   by:  
 Page size