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UnknownTailored Kidney Stone Prevention Improves Metabolic Risk Factors and Reduces Renal Colic Rate.
Not available
S-EPMC12830155 | biostudies-literature
ProteomicsFunctional characteristics of neonatal rat beta cells With distinct markers
Neonatal beta cells are considered developmentally immature and hence less glucose-responsive. To study the acquisition of mature glucose-responsiveness, we compared glucose-regulated redox state, insulin synthesis and secretion of beta cells purified from neonatal or 10-weeks old rats to their tran...
ORGANISM(S): Rattus norvegicus (Rat) 
2014-12-12 | PXD001577 | Pride
Lcmse Rat Diabetes Label free quantitation Pancreas 
TranscriptomicsGenome-wide mRNA profiling of adult human pancreatic beta and duct cells in comparison to other human tissues
Aims: establishment of reference samples to investigate gene expression selective for endocrine or ductal-exocrine cells within the adult human pancreas. To this end, human islet endocrine cells, FACS-enriched in insulin+ cells, (n=3) and human exocrine ductal cells (n=2) are compared on Affymetrix ...
ORGANISM(S): Homo sapiens 
2011-07-21 | E-GEOD-30803 | biostudies-arrayexpress
UnknownConcise Review: Markers for Assessing Human Stem Cell-Derived Implants as β-Cell Replacement in Type 1 Diabetes.
Not available
S-EPMC5031173 | biostudies-literature
UnknownMethyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.
Not available
S-EPMC2013909 | biostudies-literature
TranscriptomicsGenome-wide mRNA expression profiles of FACS-enriched rat beta cells freshly isolated from neonatal (postnatal day 2-3) and adult (10 weeks-old) Wistar rats
The lower glucose-responsiveness of neonatal beta cells is generally considered a sign of endocrine immaturity. We compared mRNA profiles of neonatal and 10-weeks old rat beta cells to see how their gene expression changes with functional maturation. Neonatal beta cells showed a lower glucose-induc...
ORGANISM(S): Rattus norvegicus 
2013-08-20 | E-GEOD-47174 | biostudies-arrayexpress
UnknownEncapsulated stem cell-derived β cells exert glucose control in patients with type 1 diabetes.
Not available
S-EPMC11471599 | biostudies-literature
TranscriptomicsPlasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming
Aims/hypothesis: Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogramming and intended to i...
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-30802 | biostudies-arrayexpress
UnknownCombining MK626, a novel DPP-4 inhibitor, and low-dose monoclonal CD3 antibody for stable remission of new-onset diabetes in mice.
Not available
S-EPMC4182446 | biostudies-literature
UnknownImmunogenicity of human embryonic stem cell-derived beta cells.
Not available
S-EPMC6518073 | biostudies-literature
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