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ProteomicsShared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice.
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated behavioural traits that include perceptual and sensory processing challenges. Notably, the severity of these sensory symptoms is often predictive of the expression of...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-15 | PXD051022 | Pride
Setd5 Superior coliculus Sensorimotor transformation Periaqueductal grey 
ProteomicsTriggering acute RyR1 Ca2+ leak leads to improved mitochondrial remodelling and function
C2C12 myotubes at day 7 of differentiation were stimulated with a single session of SIT (6 x 30s with 4 min at rest) and were immediately after the stimulation treated or not with 10 uM S107 drug for 72h. The myotubes were then harvested at 72h post stimulation (for SIT condition) and 72h post stimu...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-20 | PXD018409 | Pride
Short interval training Muscle fibers Ryanodine receptor 
UnknownTPV1, the first virus isolated from the hyperthermophilic genus Thermococcus.
Not available
S-EPMC5935114 | biostudies-literature
ProteomicsRepeated sprint training in hypoxia potentiates muscle glycolytic adaptations through S100A protein signaling
Objective: Athletes increasingly engage in repeated sprint training that consists of repeated short all-out effort interspersed by short periods of recovery. When performed in hypoxia (RSH), it may lead to greater training effects than in normoxia (RSN), however the underlying molecular mechanisms r...
ORGANISM(S): Homo sapiens (Human) 
2024-05-05 | PXD040779 | Pride
Exercise Oxphos S100a13 Rsh Glycolysis 
ProteomicsProteomics Data of "Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema" Study
Background: Chronic hand eczema (CHE) is a debilitating skin condition characterized by pain, itch, and chronic inflammation, with a complex multifactorial origin. Its diverse presentations, including overlapping traits of atopic dermatitis, contact dermatitis, and psoriasis, make diagnosis and trea...
ORGANISM(S): Homo sapiens (Human) 
2026-02-26 | PXD059218 | Pride
TranscriptomicsTranscription profiling of yeast wild type, set1delta and swd3delta SK1 diploid cells in response to sporulation conditions, in order to determine the influence of histone methylation on the meiotic transcriptome
We analysed the global gene expression profile of wild-type, set1delta and swd3delta Saccharomyces cerevisiae SK1 diploid cells in response to sporulation conditions, in order to determine the influence of histone methylation on the meiotic transcriptome.
ORGANISM(S): Saccharomyces cerevisiae 
2004-05-05 | E-MEXP-41 | biostudies-arrayexpress
TranscriptomicsKlhl6 deficiency impairs transitional B cell survival and differentiation
Klhl6 belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ domain and 4 to 6 Kelch motifs in tandem. Several of these proteins function as adaptors of the Cullin3 E3 ubiquitin ligase complex. Here we report that Klhl6 deficiency induces, as previously described, a two-fold re...
ORGANISM(S): Mus musculus 
2018-07-17 | E-MTAB-5928 | biostudies-arrayexpress
TranscriptomicsResponse of Escherichia coli to acetate in presence of 100 mM methyl α-D-glucopyranoside
This experiment was performed to challenge E. coli response to acetate when its growth rate flux is reduced by 40% with 100 mM methyl α-D-glucopyranoside. Control without inhibition in the exact same conditions was already published on ArrayExpress database (accession number E-MTAB-9086) and could ...
ORGANISM(S): Escherichia coli K-12 
2022-09-23 | E-MTAB-11717 | biostudies-arrayexpress
GenomicsThe dataset of Southeast Borneo individuals (Banjar and Ngaju ethnic groups) was used as comparative data to determine the Asian parental population of the Malagasy. Our study found strong support for an origin of the Asian ancestry of Malagasy among the Banjar.
Malagasy genetic diversity results from an exceptional proto-globalisation process that took place over a thousand years ago across the Indian Ocean. Previous efforts to locate the Asian origin of Malagasy have highlighted Borneo broadly as a potential source, but so far no firm source populations h...
EGAS00001001841 | EGA
UnknownNew insights into carbon acquisition and exchanges within the coral-dinoflagellate symbiosis under NH4+ and NO3- supply.
Not available
S-EPMC4528508 | biostudies-literature
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